@article{Macedo_Costa_Barbot_Neto_2015, place={Porto, Portugal}, title={Polycythemia vera: a case report}, volume={24}, url={https://revistas.rcaap.pt/nascercrescer/article/view/8565}, DOI={10.25753/BirthGrowthMJ.v24.i2.8565}, abstractNote={<p>Polycythemia vera (PV) is a myeloproliferative disturbance of haematopoietic cells characterized by abnormal and overstated production of erythrocytes, leukocytes and platelets. Other disease features include splenomegaly, thrombohemorrhagic complications, vasomotor disturbances, pruritus and a small risk of disease progression into acute myeloid leukemia or myelofibrosis. Thrombosis is the presenting symptom in 20% of patients with PV. It is a rare disease with an incidence of 2.3/100.000 people per year, and is even more uncommon in children and adolescents. We present a case report of a fourteen-year-old years old adolescent with clinical and laboratorial findings suggestive of polycythemia vera. Treatment with alpha-interferon was initiated. Erythrocyte and platelet count are now in the normal range. The authors make, in the context of this case report, a brief review of the criteria for the differential diagnosis of reactive thrombocytosis and myeloproliferative diseases, manifestations and treatment options.</p>}, number={2}, journal={NASCER E CRESCER - BIRTH AND GROWTH MEDICAL JOURNAL}, author={Macedo, Joana and Costa, Emília and Barbot, José and Neto, Cláudia}, year={2015}, month={Jun.}, pages={83–87} }