TY - JOUR AU - Vaz, Sara AU - Sousa, Sofia Cochito AU - Abecasis, Francisco AU - Boto, Leonor AU - Rios, Joana AU - Camilo, Cristina AU - Vieira, Marisa PY - 2018/12/28 Y2 - 2024/03/28 TI - Fluid administration − Which direction? JF - NASCER E CRESCER - BIRTH AND GROWTH MEDICAL JOURNAL JA - REVNEC VL - 27 IS - 4 SE - Original Articles DO - 10.25753/BirthGrowthMJ.v27.i4.13698 UR - https://revistas.rcaap.pt/nascercrescer/article/view/13698 SP - 11-16 AB - <p align="justify"><strong>Introduction:</strong> Although fluid administration for intravenous hydration is a common practice in pediatric age, it is not devoid of risks.<br> <strong>Methods:</strong> This was a retrospective cohort study including all children admitted to surgical recovery and receiving intravenous hydration at a Pediatric Intensive Care Unit between January and December 2015. Sodium, chloride, and base excess values were registered on two occasions: after surgery and during Unit’s hospitalization.<br> <strong>Results:</strong> Two hundred and seven children were included in the study, 66% of which, male, with a median age of 6.7 years. Fluids used consisted of 0.9% saline solution, 0.45% saline solution, and polyelectrolyte solution. The most frequently used fluids were polyelectrolyte (62%) and 0.9% saline solution (48%) at the operating room, and 0.9% saline (63%) and 0.45% saline (44%) solutions at the Pediatric Intensive Care Unit. At the operating room, 0.9% saline solution led to higher chloride median values and more negative base excess (metabolic acidosis) values compared with polyelectrolyte solution. At the Pediatric Intensive Care Unit, 0.9% saline solution administration resulted in hyperchloremia (p=0.002) and more metabolic acidosis (p=0.019) compared with 0.45% saline solution. There was no statistically significant association between type of solution used and sodium values.<br> <strong>Discussion:</strong> This study shows that the use of 0.9% saline solution is associated with development of hyperchloremic acidosis. This suggests that replacement of 0.9% saline solution with a plasma-like electrolyte solution may improve patient outcomes.</p><p align="justify">&nbsp;</p> ER -