Association between food allergy and otitis media with effusion in light of current knowledge

Authors

  • Gonçalo Mendes Department of Otorhinolaryngology and Cervicofacial Surgery, Centro Hospitalar e Universitário do Porto
  • Lise Brosseron Department Immunoallergology, Centro Hospitalar de Vila Nova de Gaia/Espinho
  • Inês Lopes Department Immunoallergology, Centro Hospitalar de Vila Nova de Gaia/Espinho
  • António Magalhães Department of Otorhinolaryngology and Cervicofacial Surgery, Centro Hospitalar e Universitário do Porto
  • Cecília Almeida e Sousa Department of Otorhinolaryngology and Cervicofacial Surgery, Centro Hospitalar e Universitário do Porto

DOI:

https://doi.org/10.25753/BirthGrowthMJ.v28.i3.15671

Keywords:

Food allergy; Otitis media with effusion; hearing loss;

Abstract

Introduction: Otitis media with effusion (OME) is a common middle ear condition in childhood with possible short- and long-term complications regarding hearing, language, cognition, and inflammatory disorders. Food allergy (FA) is also frequent in children and has a seemingly growing prevalence. It can affect several organs, including the middle ear.
Objectives: To review published literature regarding the potential association of these conditions and their relative risk.
Literature review: Allergy is a factor commonly associated with increased OME risk. Most literature on the topic focuses allergic rhinitis, due to local mechanisms potentially implicated in middle ear pathology. FA mostly affects young children, with incidence peaking at one year of age, and seems to be linked to a higher risk of other future atopic manifestations, including allergic rhinitis and asthma. OME has been proposed as an atopic manifestation in the middle ear, with several authors developing clinical studies on the subject since 1958 until present. Results have been occasionally conflicting, both regarding relative prevalence rates and presence or absence of a significant correlation between OME and FA.
Conclusions: Despite absence of consensus, OME and FA frequencies, as well as their potentially severe effects and often refractory course, highlight the need for clinicians to be alert to their potential association. Further clinical studies are required to clarify this important topic.

Downloads

Download data is not yet available.

References

1. Aydoğan B, Kiroğlu M, Altintas D, Yilmaz M, Yorgancilar E, Tuncer U. The role of food allergy in otitis media with effusion. Otolaryngol Head Neck Surg. 2004; 130:747-50.

2. Dӧner F, Yariktas M, Demirci M. The role of allergy in recurrent otitis media with effusion. J Investig Allergol Clin Immunol. 2004; 14:154-8.

3. Williamson I. Otitis media with effusion in children. BMJ Clin Evid. 2011; 2011. pii: 0502.

4. Ruokonen J, Paganus A, Lehti H. Elimination diets in the treatment of secretory otitis media. International journal of pediatric otorhinolaryngology. 1982; 4:39-46.

5. Haywood M, Alade A, Vijendren A, Singh P. Late presentation of egg white and milk protein allergy as rhinitis and otitis media. British journal of hospital medicine. 2017; 78:112-3.

6. Tos M. Epidemiology and natural history of secretory otitis. Otology & Neurotology. 1984; 5: 459-62.

7. Shekelle P, Takata G, Chan LS, Mangione-Smith R, Corley PM, Morphew T, et al. Diagnosis, natural history, and late effects of otitis media with effusion. Evid Rep Technol Assess (Summ). 2002; 55:1-5.

8. Correia A. O desenvolvimento fonológico de crianças com otites médias com derrame: estudo longitudinal. 2015.

9. Maris M, Wojciechowski M, Van de Heyning P, Boudewyns A. A cross-sectional analysis of otitis media with effusion in children with Down syndrome. Eur J Pediatr. 2014; 173:1319-25.

10. Paradise JL, Rockette HE, Colborn DK, Bernard BS, Smith CG, Kurs-Lasky M, et al. Otitis media in 2253 Pittsburgh-area infants: prevalence and risk factors during the first two years of life. Pediatrics. 1997; 99:318-33.

11. Williamson IG, Dunleavey J, Bain J, Robinson D. The natural history of otitis media with effusion–a three-year study of the incidence and prevalence of abnormal tympanograms in four South West Hampshire infant and first schools. J Laryngol Otol. 1994; 108:930-4.

12. Rosenfeld RM, Schwartz SR, Pynnonen MA, Tunkel DE, Hussey HM, Fichera JS, et al. Clinical practice guideline: tympanostomy tubes in children. Otolaryngol Head Neck Surg. 2013; 149:S1-35.

13. Brower CNM, Maille AR, Rovers MM , Grobbee DE, Sanders EAM, Schilder AGM. Health-related quality of life in children with otitis media. International journal of pediatric otorhinolaryngology. 2005; 69:1031-41.

14. Sampson HA, Aceves S, Bock SA, James J, Jones S, Lang D, et al.
Food allergy: a practice parameter update—2014. J Allergy Clin
Immunol. 2014; 134:1016-25.e43.

15. Osborne NJ, Koplin JJ, Martin PE, Gurrin LC, Lowe AJ, Matheson MC, et al. Prevalence of challenge-proven IgE mediated food allergy using population-based sampling and predetermined challenge criteria in infants. J Allergy Clin Immunol. 2011; 127:668-76.e1-2

16. Jackson KD, Howie LD, Akinbami OJ. Trends in allergic conditions among children: United States, 1997-2011. NCHS Data Brief. 2013:1-8.

17. Woicka-Kolejwa K, Zaczeniuk M, Majak P, Pawłowska-Iwanicka K, Kopka M, Stelmach W, et al. Food allergy is
associated with recurrent respiratory tract infections during childhood. Advances in Dermatology and Allergology/Postȩpy Dermatologii i Alergologii. 2016; 33:109-13.

18. Allen JK, Koplin JJ. The epidemiology of IgE-mediated food allergy and anaphylaxis. Immunol Allergy Clin N Am. 2012; 32:35-50.

19. Wood RA. Food allergy in children: prevalence, natural history and monitoring for resolution. UpToDate online. Accessed Oct, 2018.

20. Sicherer SH. Respiratory manifestations of food allergy. UpToDate online. Accessed Oct, 2018.

21. Bernstein JM. Role of allergy in eustachian tube blockage and otitis media with effusion: a review. Otolaryngology-head and neck surgery. 1996; 114: 562-8.

22. Marseglia G, Pagella F, Caimmi D, Caimmi S, Castellazzi AM, Poddighe D, et al. Increased risk of otitis media with effusion in allergic children presenting with adenoiditis. Otolaryngology – Head and Neck Surgery. 2008; 138: 572-5.

23. Luong A, Roland PS. The link between allergic rhinitis and chronic otitis media with effusion in atopic patients. Otolaryngologic Clinics of North America. 2008; 41: 311-23.

24. Bernstein JM. The role of IgE-mediated hypersensitivity in the development of otitis media with effusion. Otolaryngologic Clinics of North America. 1992; 25:197-211.

25. Zermotti M, Pawankar R, Ansotegui I, Badellino H, Croce JS, Hossny E, et al. Otitis media with effusion and atopy: is there a causal relationship?. World Allergy Organization Journal. 2017; 10:37.

26. Ramakrishnan JB. The role of food allergy in otolaryngology disorders. Current opinion in otolaryngology & head and neck surgery. 2010; 18:195-9.

27. Hurst DS, Venge P. The impact of atopy on neutrophil activity in middle ear effusion from children and adults with chronic otitis media. Archives of Otolaryngology–Head & Neck Surgery. 2002; 128:561-6.

28. Doyle WJ. The link between allergic rhinitis and otitis media. Current opinion in allergy and clinical immunology. 2002; 2:21-5.

29. Yamashita T, Okazaki N, Kumazawa T. Relation between Nasal and Middle Ear Allergy Experimental Study. Annals of Otology, Rhinology & Laryngology. 1980; 89: 147-52.

30. Solow IA. Is serous otitis media due to allergy or infection. Annals of allergy. 1958; 16:297.

31. Lecks HI. Allergic aspects of serous otitis media in childhood. New York state journal of medicine. 1961; 61:2737.

32. Viscomi GJ. Allergic secretory otitis media: an approach to management. The Laryngoscope. 1975; 85:751-8.

33. Nsouli TM, Nsouli SM, Linde RE, O’Mara F, Scanlon RT, Bellanti JA. Role of food allergy in serous otitis media. Annals of allergy. 1994; 73:215-9.

34. Corey JP, Adham RE, Abbass AH, Seligman I. The role of IgEmediated hypersensitivity in otitis media with effusion. American journal of otolaryngology. 1994; 15:138-44.

35. Reisman RE, Bernstein J. Allergy and secretory otitis media: clinical and immunologic studies. Pediatric Clinics of North America. 1975; 22:251-7.

36. Bluestone CD. Eustachian tube function and allergy in otitis media. Pediatrics. 1978; 61: 753-60.

37. McGovern JP, Haywood TJ, Fernandez A. Allergy and secretory otitis media: an analysis of 512 cases. JAMA. 1967; 200:124-8.

38. Derebery MJ, Berliner KI. Allergic eustachian tube dysfunction: diagnosis and treatment. The American journal of otology. 1997; 18:160-5.

39. Juntti H, Tikkanen S, Kokkonen J, Alho OP, Niinimäki A. Cow’s milk allergy is associated with recurrent otitis media during childhood. Acta Otolaryngol. 1999; 119:867-73.

Downloads

Published

2019-10-14

How to Cite

1.
Mendes G, Brosseron L, Lopes I, Magalhães A, Almeida e Sousa C. Association between food allergy and otitis media with effusion in light of current knowledge. REVNEC [Internet]. 2019Oct.14 [cited 2024Mar.28];28(3):126-31. Available from: https://revistas.rcaap.pt/nascercrescer/article/view/15671

Issue

Section

Review Articles

Most read articles by the same author(s)