Disease modelling and drug development with iPSC-derived cells: a brave new world?

Authors

  • Natália Oliva-Teles Centro de Genética Médica Jacinto de Magalhães; Centro Hospitalar Universitário do Porto; Unit for Multidisciplinary Research in Biomedicine, Instituto de Ciências Biomédicas Abel Salazar, Universidade do Porto (UMIB/ICBAS, UP)

DOI:

https://doi.org/10.25753/BirthGrowthMJ.v29.i1.19728

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References

NIH Stem Cell Information Home Page. In Stem Cell Information [World Wide Web site]. Bethesda, MD: National Institutes of Health, U.S. Department of Health and Human Services, 2016 [cited March 23, 2020] Available at https://stemcells.nih.gov/info/basics/6.htm.

Elitt MS, Barbar L, Tesar PJ. Drug screening for human genetic diseases using iPSC models. Human Molecular Genetics. 2018; 27:R89–R98.

Karagiannis P, Takahashi K, Saito M, Yoshida Y, Okita K, Watanabe A, et al. Induced pluripotent stem cells and their use in human models of disease and development. Physiol Rev. 2019; 99:79-114.

Ilic D, Devito L, Miere C, Codognotto S. Human embryonic and induced pluripotent stem cells in clinical trials. British Medical Bulletin, 2015, 116:19–27.

Yamanaka S. Induced Pluripotent Stem Cells: Past, Present, and Future. Cell Stem Cell. 2012; 10:678-84.

Ustyantseva EI, Medvedev SP, Vetchinova AS, Illarioshkin SN, Leonov SV, Zakian SM. Generation of an induced pluripotent stem cell line, ICGi014-A, by reprogramming peripheral blood mononuclear cells from a patient with homozygous D90A mutation in SOD1 causing Amyotrophic lateral sclerosis. Stem Cell Res. 2020; 42:101675.

Rodríguez-Traver E, Díaz-Guerra E, Rodríguez C, Arenas F, Orera M, Kulisevsky J, A collection of three integration-free iPSCs derived from old male and female. Stem Cell Research. 2020; 42: 101663.

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Published

2020-03-24

How to Cite

1.
Oliva-Teles N. Disease modelling and drug development with iPSC-derived cells: a brave new world?. BGMJ [Internet]. 2020 Mar. 24 [cited 2025 Dec. 10];29(1):7-8. Available from: https://revistas.rcaap.pt/bgmj/article/view/19728

Issue

Vol. 29 No. 1 (2020)

Section

Editorial

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