Disseminated tuberculosis in an infant – Case report

Authors

DOI:

https://doi.org/10.25753/BirthGrowthMJ.v32.i2.23772

Keywords:

infant, Mycobacterium tuberculosis, Pediatrics, tuberculosis

Abstract

Infants are a particularly vulnerable group for the development of severe and/or extrapulmonary forms of tuberculosis. The difficulty in establishing a definitive and timely diagnosis contributes to the high morbimortality in this age group. Investigation often relies on a high index of suspicion. Herein is reported a case of disseminated tuberculosis in an infant that highlights its clinical complexity and diagnostic challenge.

Downloads

Download data is not yet available.

References

Berti E; Galli L; Venturini E; de Martini M; Chiapinni E. Tuberculosis in childhood: a systematic review of national and international guidelines. BMC Infectious Diseases. 2014; 14:1471-2334.

Cruz AT; Starke; JR. Pediatric Tuberculosis. Pediatrics in Review. 2010 31;13.

American Thoracic Society. Diagnostic Standards and Classification of Tuberculosis in Adults and Children. Am J Respir Crit Care Med. 2000;161:1376–95.

Leonard JM. Central Nervous System Tuberculosis. Microbiol Spectr 2017; 5.

World Health Organization. Global tuberculosis report 2019. (Assessed August 20; 2020) Available at: https://www.who.int/tb/publications/global_report/en/ (Accessed on march 31; 2020).

Portugal. Ministério da Saúde. Direção-Geral da Saúde. Tuberculose em Portugal - Desafios e Estratégias 2018. Lisboa: Direção-Geral da Saúde; 2018. (Assessed May 15; 2020) Available at: https://www.dgs.pt/portal-da-estatistica-da-saude/diretorio-de-informacao/diretorio-de-informacao/por-serie-963621-pdf.aspx?v=11736b14-73e6-4b34-a8e8-d22502108547.

Direção-Geral da Saúde. Estratégia de vacinação contra a tuberculose com a vacina BCG. Norma nº 006/2016. (Assessed May 29; 2021). Available at: https://www.dgs.pt/directrizes-da-dgs/normas-e-circulares-normativas/norma-n-0062016-de-29062016-pdf.aspx.

Luzzati R.; Migliori G B; Zignol M; Cirillo D M; Maschio M.; Tominz R.; Confalonieri M. Children under 5 years are at risk for tuberculosis after occasional contact with highly contagious patients: outbreak from a smear-positive healthcare worker. European Respiratory Journal. 2017 50(5); 1701414.

Starke JR. New concepts in childhood tuberculosis. Curr Opin Pediatr. 2007 19:306.

Nelson LJ; Wells CD. Global epidemiology of childhood tuberculosis. Int J Tuberc Lung Dis 2004 8:636.

Thomas T A; Heysell S K; Moodley P; Montreuil R; Ha X; Friedland G; Shah S. Intensified specimen collection to improve tuberculosis diagnosis in children from Rural South Africa; an observational study. BMC Infectious Diseases. 2014 14(1).

Schaaf HS; Marais BJ; Carvalho I; et al. Challenges in childhood tuberculosis. In: Migliori GB; Bothamley G; Duarte R; et al.; eds. Tuberculosis (ERS Monograph). Sheffield; European Respiratory Society. 2018 p.234–62.

Stop TB Partnership Childhood TB Subgroup World Health Organization. Guidance for National Tuberculosis Programmes on the management of tuberculosis in children. Chapter 1: introduction and diagnosis of tuberculosis in children. Int J Tuberc Lung Dis 2006; 10:1091.

Lighter J; Rigaud M. Diagnosing childhood tuberculosis: traditional and innovative modalities. Curr Probl Pediatr Adolesc Health Care. 2009 39:61.

Downloads

Published

2023-09-14

How to Cite

1.
Abreu AM, Miranda S, Carvalho I, Gonçalves A, Branco L, Barros D, et al. Disseminated tuberculosis in an infant – Case report. BGMJ [Internet]. 2023 Sep. 14 [cited 2026 Jan. 13];32(2):122-6. Available from: https://revistas.rcaap.pt/bgmj/article/view/23772

Issue

Vol. 32 No. 2 (2023)

Section

Clinical Case Reports

License

Copyright (c) 2023 Ana Margarida Abreu, Sofia Miranda, Isabel Carvalho, Augusta Gonçalves, Liliana Branco, Daniela Barros, Marina Pinheiro

Creative Commons License

This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

All articles published in the Birth and Growth Medical Journal are Open Access and meet the requirements of funding agencies and academic institutions. Third-party use of published content is permitted under the terms of the Creative Commons Attribution-NonCommercial (CC BY-NC) license. It is the responsibility of authors to obtain permission for reproducing figures, tables, or other materials from previously published works.

Authors must submit a Conflict of Interest statement and an Authorship Form together with their manuscript. A confirmation email will be sent to the corresponding author upon receipt of the submission. Authors are also permitted to deposit their articles in institutional or personal repositories, provided that the original publication in the Birth and Growth Medical Journal is clearly indicated and the terms of the Creative Commons license are respected.