The impact of Potocki-Lupski syndrome on sibling relationships

Authors

  • Marta Antunes Department of Child and Adolescent Psychiatry. Centro Materno-Infantil do Norte, Centro Hospitalar Universitário de Santo António https://orcid.org/0000-0003-2726-9408
  • Mariana Liz Department of Child and Adolescent Psychiatry. Centro Materno-Infantil do Norte, Centro Hospitalar Universitário de Santo António
  • Zulmira Correia Department of Child and Adolescent Psychiatry. Centro Materno-Infantil do Norte, Centro Hospitalar Universitário de Santo António

DOI:

https://doi.org/10.25753/BirthGrowthMJ.v32.i1.25110

Keywords:

behavior problem, healthy sibling, intellectual disability, Potocki-Lupski syndrome

Abstract

Introduction: Potocki-Lupski syndrome is a condition characterized by cognitive, behavioral, and medical manifestations caused by 17p11.2 duplication encompassing the RAI1 gene. Due to the significance that sibling relations acquire throughout life, changes in the health and functioning of one sibling affect the others.
Case report: A 14-year-old boy, healthy sibling of a girl with Potocki-Lupski syndrome, attended the Child and Adolescent Psychiatry consultation due to maternal concerns about the impact of the sister’s disease on his well-being. On observation, despite looking relatively well adapted to the sister‘s condition, the boy showed sadness and shame regarding some of the sister‘s behaviors, particularly when occurring in public places, and great guilt towards them.
Discussion/conclusion: The impact of the intellectual disability of a child on healthy siblings comprises negative and positive experiences. Therefore, it should be assessed in light of a network of influences and idiosyncrasies characteristic of family relationships.

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References

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Published

2023-06-23

How to Cite

1.
Antunes M, Ferraz de Liz M, Correia Z. The impact of Potocki-Lupski syndrome on sibling relationships. BGMJ [Internet]. 2023 Jun. 23 [cited 2025 Dec. 10];32(1):41-4. Available from: https://revistas.rcaap.pt/bgmj/article/view/25110

Issue

Vol. 32 No. 1 (2023)

Section

Clinical Case Reports

License

Copyright (c) 2023 Marta Antunes, Mariana Liz, Zulmira Correia

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