Dermatology clinical case

Authors

  • Vera Gonçalves Department of Pediatrics, Unidade Local de Saúde do Alto Minho
  • André Costa e Silva Department of Pediatrics, Unidade Local de Saúde do Alto Minho
  • André Azevedo Department of Pediatrics, Unidade Local de Saúde do Alto Minho https://orcid.org/0000-0001-8530-1803
  • Isabel Martinho Department of Pediatrics, Unidade Local de Saúde do Alto Minho
  • Sandrina Martins Department of Pediatrics, Unidade Local de Saúde do Alto Minho https://orcid.org/0000-0002-8853-9099
  • Vera Teixeira Department of Dermatology, Unidade Local de Saúde do Alto Minho https://orcid.org/0000-0002-7708-0753

DOI:

https://doi.org/10.25753/BirthGrowthMJ.v32.i4.26261

Keywords:

erythema multiforme, mycoplasma pneumoniae, mycoplasma pneumoniae-induced rash and mucositis, Stevens-Johnson syndrome, toxic epidermal necrolysis

Abstract

The authors report the case of an eight-year-old boy who presented to the Pediatric Emergency Department for severe oral mucositis, fever, purulent conjunctivitis, and skin rash. The diagnosis of Mycoplasma pneumoniae-induced rash and mucositis (MIRM) was established. Extrapulmonary complications of Mycoplasma pneumoniae infections are increasingly recognized. Over the years, patients with mucocutaneous manifestations have been misdiagnosed with erythema multiforme spectrum disease. In 2015, MIRM was proposed as a distinct clinical entity with unique pathophysiology, clinical manifestations, and prognosis.

Downloads

Download data is not yet available.

References

Waites KB, Talkington DF. Mycoplasma pneumoniae and its role as a human pathogen. Clin Microbiol Rev. 2004;17(4):697-728.

Canavan TN, Mathes EF, Frieden I, Shinkai K. Mycoplasma pneumoniae-induced rash and mucositis as a syndrome distinct from Stevens-Johnson syndrome and erythema multiforme: a systematic review. J Am Acad Dermatol. 2015;72(2):239-45.

Meyer Sauteur PM, Theiler M, Buettcher M, Seiler M, Weibel L, Berger C. Frequency and Clinical Presentation of Mucocutaneous Disease Due to Mycoplasma pneumoniae Infection in Children With Community-Acquired Pneumonia. JAMA Dermatol. 2019;156(2):144-50.

Shah PR, Williams AM, Pihlblad MS, Nischal KK. Ophthalmic Manifestations of Mycoplasma-Induced Rash and Mucositis. Cornea. 2019;38(10):1305-8.

Brazel D, Kulp B, Bautista G, Bonwit A. Rash and Mucositis Associated With Mycoplasma pneumoniae and Chlamydophila pneumoniae: A Recurrence of MIRM? J Pediatric Infect Dis Soc. 2020.

Martínez-Pérez M, Imbernón-Moya A, Lobato-Berezo A, Churruca-Grijelmo M. Mycoplasma pneumoniae-Induced Mucocutaneous Rash: A New Syndrome Distinct from Erythema Multiforme? Report of a New Case and Review of the Literature. Actas Dermosifiliogr. 2016;107(7):e47-51.

Santos RP, Silva M, Vieira AP, Brito C. Mycoplasma pneumoniae-induced rash and mucositis: a recently described entity. BMJ Case Rep. 2017;2017.

Downloads

Published

2024-01-23

How to Cite

1.
Gonçalves V, Costa e Silva A, Azevedo A, Martinho I, Martins S, Teixeira V. Dermatology clinical case. BGMJ [Internet]. 2024 Jan. 23 [cited 2025 Dec. 9];32(4):323-5. Available from: https://revistas.rcaap.pt/bgmj/article/view/26261

Issue

Vol. 32 No. 4 (2023)

Section

Image Cases

License

Copyright (c) 2024 Vera Gonçalves, André Costa e Silva, André Azevedo, Isabel Martinho, Sandrina Martins, Vera Teixeira

Creative Commons License

This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

All articles published in the Birth and Growth Medical Journal are Open Access and meet the requirements of funding agencies and academic institutions. Third-party use of published content is permitted under the terms of the Creative Commons Attribution-NonCommercial (CC BY-NC) license. It is the responsibility of authors to obtain permission for reproducing figures, tables, or other materials from previously published works.

Authors must submit a Conflict of Interest statement and an Authorship Form together with their manuscript. A confirmation email will be sent to the corresponding author upon receipt of the submission. Authors are also permitted to deposit their articles in institutional or personal repositories, provided that the original publication in the Birth and Growth Medical Journal is clearly indicated and the terms of the Creative Commons license are respected.

Most read articles by the same author(s)