Hypernatraemic Dehydration in a Newborn
Keywords:
breastfeeding, hypernatraemic dehydration, infant health, lactation support, neonateAbstract
Introduction: The World Health Organization recommends initiating breastfeeding within the first hour of birth and exclusively breastfeeding for the first six months. This practice reduces the risk of infant illnesses such as diarrhoea and pneumonia and benefits mothers by lowering the risk of postpartum haemorrhage and certain cancers. Successful breastfeeding depends on factors like milk production, effective infant latch, maternal mental health, and support systems. Difficulties with breastfeeding can lead to serious neonatal complications, including hypernatraemic dehydration, defined as a serum sodium level above 145 mEq/L.
Case Report: We present a case of a 10-day-old male neonate, born at term by caesarean section after an uneventful pregnancy except for third trimester oligohydramnios. Despite initial breastfeeding attempts, the infant developed significant weight loss, reduced bowel movements, and decreased urine output by the tenth day of life. Upon admission, he had lost 26% of his birth weight, appeared cachectic, and exhibited signs of severe dehydration. Laboratory tests confirmed hypernatraemia (serum sodium concentration of 156 mEq/L). Immediate treatment with formula feeding and intravenous fluids resulted in normalization of serum sodium levels within 18 hours, and the infant regained his birth weight by day 17 of life.
Discussion: Hypernatraemia in neonates, particularly when related to breastfeeding difficulties, is a critical condition that can cause severe neurological and systemic complications. The rising incidence of hypernatraemia associated with exclusive breastfeeding underscores the need for adequate lactation support and close monitoring. Early hospital discharge without proper breastfeeding counselling significantly increases this risk.
Conclusion: While breastfeeding promotion is vital for public health, ensuring adequate support and monitoring is essential to prevent complications such as hypernatraemic dehydration. Close follow-up, regular weight monitoring, and access to professional lactation support are crucial for safeguarding the health of both infants and mothers.
Downloads
References
Victora CG, Bahl R, Barros AJ, et al. Breastfeeding in the 21st century: epidemiology, mechanisms, and lifelong effect. Lancet. 2016;387(10017):475–490. doi: https://doi.org/10.1016/S0140-6736(15)01024-7.
Horta BL, Loret de Mola C, Victora CG. Breastfeeding and intelligence: a systematic review and meta-analysis. Acta Paediatr. 2015 Dec;104(467):14-9. doi: https://doi.org/10.1111/apa.13139.
Chowdhury R, Sinha B, Sankar MJ. et al. 2015. Breastfeeding and maternal health outcomes: a systematic review and meta-analysis. Acta Paediatrica 104: 96–113.
Mundagowa PT, Chadambuka EM, Chimberengwa PT, et al. Barriers and facilitators to exclusive breastfeeding practices in a disadvantaged community in Southern Zimbabwe: a maternal perspective. World Nutr. 2021;12(1):73–91. doi: https://doi.org/10.26596/wn.202112173-91.
Renfrew MJ, McCormick FM, Wade A, Quinn B, Dowswell T. Support for healthy breastfeeding mothers with healthy term babies. Cochrane Database Syst Rev. 2012. p. CD001141. DOI: https://doi.org/10.1002/14651858.CD001141.pub4.
Livingstone VH. Problem-solving formula for failure to thrive in breast-fed infants. Can Fam Physician. 1990;36:1541–5.
Ogbe Z, Andegiorgish AK, Zeray AH, Zeng L. Neonatal Hypernatremic Dehydration Associated with Lactation Failure. Case Rep Crit Care. 2020 Nov 15;2020:8879945. doi: https://doi.org/10.1155/2020/8879945.
Bhat SR, Lewis P, David A, et al. Dehydration and hypernatremia in breast-fed term healthy neonates. Indian J Pediatr. 2006;73(1):39–41. PMID: 16444059. doi: https://doi.org/10.1007/BF02758258.
Adrogué HJ, Madias NE. Hypernatremia. N Engl J Med. 2000;342(20):1493–9.
Unal S, Arhan E, Kara N, Uncu N, Aliefendioğlu D. Breast-feeding-associated hypernatremia: retrospective analysis of 169 term newborns. Pediatr Int. 2008;50(1):29–34.
Kaplan JA, Siegler RW, Schmunk GA. Fatal hypernatremic dehydration in exclusively breast-fed newborn infants due to maternal lactation failure. Am J Forensic Med Pathol. 1998;19:19–22.
Das JC. Hypernatremic dehydration in newborn infants: a review. Ulutas Med J. 2015;1(2):22-25.doi: https://doi.org/10.5455/umj.201506181158472.
Boskabadi H, Maamouri G, Ebrahimi M, Ghayour-Mobarhan M, Esmaeily H, Sahebkar A, et al. Neonatal hypernatremia and dehydration in infants receiving inadequate breastfeeding. Asia Pac J Clin Nutr 2010;19:301-7.
Picciano MF. Nutrient composition of human milk Pediatr Clin North Am. 2001;48:53–67.
Koo WW, Gupta JM. Breast milk sodium Arch Dis Child. 1982;57:500–2.
Harding D, Moxham J, Cairns P. Weighing alone will not prevent hypernatraemic dehydration Arch Dis Child Fetal Neonatal Ed. 2003;88:F349.
Marcdante KJ, Kliegman RM. Nelson essentials of pediatrics. 7th ed. Philadelphia: Saunders; 2015.
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2026 Joana Filipa Ventura Lourenço, Beatriz Carmo, Beatriz Vieira, Ana Luísa Santos, Isabel Mendes

This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
All articles published in the Birth and Growth Medical Journal are Open Access and meet the requirements of funding agencies and academic institutions. Third-party use of published content is permitted under the terms of the Creative Commons Attribution-NonCommercial (CC BY-NC) license. It is the responsibility of authors to obtain permission for reproducing figures, tables, or other materials from previously published works.
Authors must submit a Conflict of Interest statement and an Authorship Form together with their manuscript. A confirmation email will be sent to the corresponding author upon receipt of the submission. Authors are also permitted to deposit their articles in institutional or personal repositories, provided that the original publication in the Birth and Growth Medical Journal is clearly indicated and the terms of the Creative Commons license are respected.