WEARING RED – A CASE OF DRUG REACTION
Keywords:Aromatic anticonvulsants, carbamazepine, drug reaction
Introduction: Drug reactions may be limited to a skin rash, or present as a multisystemic syndrome with a variable prognosis such as DRESS (Drug Reaction with Eosinophilia and Systemic Symptoms) syndrome.
Case report: The authors report a case of a girl admitted to the Emergency Department due to prolonged fever with generalised rash and pruritus, and prominent soft tissue edema of face, legs and arms, six weeks after beginning treatment with carbamazepine. Laboratory results showed eosinophilia and elevated liver enzymes. After stopping the drug we assisted to both clinical and analytical normalization.
Discussion: The early recognition of DRESS syndrome and drug withdrawal allowed a favourable evolution of a potentially fatal entity.
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