Effect of methylphenidate in a child with pica and attention-deficit/hyperactivity disorder
DOI:
https://doi.org/10.25753/BirthGrowthMJ.v32.i1.25449Keywords:
attention-deficit/hyperactivity disorder, child, Methylphenidate, picaAbstract
Introduction: Pica and attention-deficit/hyperactivity disorder (ADHD) comorbidity has rarely been described in the literature. It has been suggested that pica and ADHD may share some neurobiological ground and that methylphenidate may be a reasonable treatment option for these patients.
Case report: Herein is reported the case of an eight-year-old boy with pica and ADHD who was successfully treated with methylphenidate. Notably, both disorders relapsed when methylphenidate was discontinued, with symptom control regained after its reintroduction.
Discussion: ADHD and pica may share features such as poor impulse control and dopaminergic system dysfunction, with several studies suggesting that dopamine may be the implicated neurotransmitter.
Conclusion: This case report adds to the existing body of evidence suggesting that methylphenidate is effective in pica and AHDH comorbidity. Nevertheless, there is a need for further research to better understand the effects of methylphenidate on pica.
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References
American Psychiatric Association DSM-5 Task Force. Diagnostic and statistical manual of mental disorders: DSM-5. 5th ed. Washington, DC: American Psychiatric Association; 2013.
Leung AKC, Hon KL. Pica: A Common Condition that is Commonly Missed - An Update Review. Curr Pediatr Rev. 2019;15(3):164–9.
McNaughten B, Bourke T, Thompson A. Fifteen-minute consultation: the child with pica. Arch Dis Child Educ Pract Ed. 2017;102(5):226–9.
Aloni MN, Lecerf P, Lê P-Q, Heijmans C, Huybrechts S, Devalck C, et al. Is Pica under-reported in children with sickle cell disease? A pilot study in a Belgian cohort. Hematology. 2015;20(7):429–32.
Hagopian LP, Rooker GW, Rolider NU. Identifying empirically supported treatments for pica in individuals with intellectual disabilities. Res Dev Disabil. 2011;32(6):2114–20.
Sturmey P. Pica and developmental disability. The Journal of the American Board of Family Practice. 2001; 14: 80–1.
Gunes H, Tanidir C, Adaletli H, Uneri OS. Effect of Methylphenidate on Impulsivity in a Child with Pica and Attention Deficit Hyperactivity Disorder. Klin Psikofarmakol Bülteni-Bulletin Clin Psychopharmacol [Internet]. 2016;26(1):87–8. Available from: https://doi.org/10.5455/bcp.20151013010546.
Del Campo N, Chamberlain SR, Sahakian BJ, Robbins TW. The roles of dopamine and noradrenaline in the pathophysiology and treatment of attention-deficit/hyperactivity disorder. Biol Psychiatry. 2011;69(12):e145-57.
Cardoso D, Duarte L, Pinto VF, Cartaxo T. Pica and attention deficit hyperactivity disorder: is there a link? Comorbidity and treatment outcomes with methylphenidate. Nascer e Crescer – Birth Growth Med J [Internet]. 2021;30(1):12–7. Available from: https://revistas.rcaap.pt/nascercrescer/article/view/18910.
Gautam P, Bhatia MS, Rathi A. Intellectual disability and multiple co morbid psychiatric disorders in a child: a case report. J Clin Diagn Res [Internet]. 2014/11/20. 2014 Nov;8(11):WD01-WD2. Available from: https://pubmed.ncbi.nlm.nih.gov/25584292.
Hergüner S, Hergüner AS. Pica in a child with attention deficit hyperactivity disorder and successful treatment with methylphenidate. Prog Neuropsychopharmacol Biol Psychiatry. 2010;34(6):1155-6. doi: https://doi.org/10.1016/j.pnpbp.2010.06.005.
Hergüner S, Ozyildirim I, Tanidir C. Is Pica an eating disorder or an obsessive-compulsive spectrum disorder? Vol. 32, Progress in neuro-psychopharmacology & biological psychiatry. England; 2008. p. 2010–1.
Singh NN, Ellis CR, Crews WD, Singh YN. Does Diminished Dopaminergic Neurotransmission Increase Pica? J Child Adolesc Psychopharmacol [Internet]. 1994;4(2):93–9. Available from: https://doi.org/10.1089/cap.1994.4.93.
Brahm NC, Farmer KC, Brown RC. Pica episode reduction following initiation of bupropion in a developmentally disabled adult. The Annals of pharmacotherapy. 2006; 40: 2075–6.
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