Hypernatremic dehydration in newborn infants
DOI:
https://doi.org/10.25753/BirthGrowthMJ.v25.i1.8823Keywords:
hypernatremia, dehydration, neonates, risk factor, breastfeedingAbstract
Hypernatremia occurred frequently erstwhile when infant formula with high sodium concentration were given to neonates. Today, the most common cause of hypernatremic dehydration in the healthy term newborn is the low volume intake of breast milk.
The diagnosis is usually performed accidentally in cases of important weight loss in the newborn. Other clinical manifestations, when present, are usually nonspecific, with prevalence of neurologic symptoms that reflect intracellular dehydration.
Some complications, especially seizures, occur most frequently during treatment. Therefore, the management and treatment of this condition should be cautious and requires a thorough understanding of the underlying hydroelectrolytic disorder to prevent the brain cells´ overhydration.
The practitioners should continue to recommend breastfeeding as the best method of nourishing healthy infants. There should be a high level of suspicion and early recognition of the underlying breastfeeding problems before the onset of serious and sometimes life-threatening dehydration.
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References
Pelleboer RA, Bontemps ST, Verkerk PH, Van Dommelen P, Pereira RR, Van Wouwe JP. A nationwide study on hospital admissions due to dehydration in exclusively breastfed infants in the Netherlands: its incidence, clinical characteristics, treatment and outcome. Acta Paediatr 2009; 98: 807-11.
Boskabadi H, Maamouri G, Ebrahimi M, Ghayour-Mobarhan M, Esmaeily H, Sahebkar A, et al. Neonatal hypernatremia and dehydration in infants receiving inadequate breastfeeding. Asia Pac J Clin Nutr 2010; 19; 301-7.
Krishnamurthy S, Debnath S, Gupta G. Breast feeding-associated hypernatremic dehydration: A preventable tragedy in newborn infants. Journal of Case Reports 2011; 1: 1-5.
Jain S, Basu S. Hypernatremic dehydration in term and near-term neonates. Indian J Pediatr 2010; 77: 461.
Leung C, Chang WC, Yeh SJ. Hypernatremic dehydration due to concentrated infant formula: report of two cases. Pediatr Neonatol 2009; 50: 70-3.
Fawke J, Whitehouse WP, Kudumula V. Monitoring of newborn weight, breast feeding and severe neurological sequelae secondary to dehydration. Arch Dis Child 2008; 93: 264-5.
Asturizaga DA, Mazzi E. Hipernatremia neonatal: factores de riesgo. Arch Pediatr Urug 2011; 82:110-4.
Unal S, Arhan E, Kara N, Uncu N, Aliefendio D. Breast-feeding-associated hypernatremia: Retrospective analysis of 169 term newborns. Pediatrics International 2008; 50:29–34.
Akcan, Barış A. Hypernatraemia in a newborn because of salting of the skin. Journal of Paediatrics and Child Health 2011; 47:316-7.
Greenbaum LA. Electrolyte and acid-base disorders. In: Kliegman RM, Stanton B, Geme J, Schor N, Behrman RE, editors. Nelson Textbook of Paediatrics. 20th ed. Philadelphia: Elsevier Health Sciences 2015; 55: 351-3.
Chung CH. Zimmerman D. Hypernatremia and Hyponatremia: Current Understanding and Management. Clinical Pediatric Emergency Medicine 2009; 10:272-8.
Gouveia C, Adelaide O. Problemas comuns da amamentação. Rev Port Clin Geral 2009; 25:370-5.
Chisti MJ, Pietroni MA, Alom MS, Smith JH. Use of only oral rehydration salt solution for successful management of a young infant with serum sodium of 201 mmol/L in an urban diarrhoeal diseases hospital, Bangladesh. Journal of Health Population and Nutrition 2012; 30:371-6
Fang C, Mao J, Dai Y, Xia Y, Fu H, Chen Y, et al. Fluid management of hypernatraemic dehydration to prevent cerebral oedema: a retrospective case control study of 97 children in China. J Paediatr Child Health 2010; 46:301-3.
Verbalis, J.G. Brain volume regulation in response to changes in osmolality. Neuroscience 2010; 168:862-70.
Goff DA, Higinio V. Hypernatremia. Pediatrics in Review 2009; 30:412-3.
Schwaderer A, Schwartz G. Treating hypernatremic dehydration. Peds in Rev 2005; 26:148-50.
El-Bayoumi MA, Abdelkader AM, El-Assmy MM, Alwakeel AA, El-Tahan HM. Normal saline is a safe initial rehydration fluid in children with diarrhea-related hypernatremia. Eur J Pediatr 2012; 171:383-8.
Laing IA. Hypernatraemic dehydration in newborn infants. Acta Pharmacol Sin 2002; 23:48-51.
Rand SE, Kolberg A. Neonatal Hypernatremic Dehydration Secondary to Lactation Failure. J Am Board Fam Med 2001; 14:155-8.
Moritz ML, Ayus JC. Disorders of Water Metabolism in Children: Hyponatremia and Hypernatremia. Pediatrics in Review 2002; 23:371-80.
Finberg L. Dehydration in Infancy and Childhood. Pediatrics in Review 2002; 23:277-82.
Huang LH, Anchala KR, Ellsbury DL, George CS. Dehydration Treatment & Management. [Internet]. 2014 Sept 25. Available from: http://emedicine.medscape.com/article/906999.
Ramirez PL, Emre U, Giambruno C. Index of Suspicion in the Nursery. NeoReviews 2005; 6: 399-402.
American Academy of Pediatrics Section on Breastfeeding. Breastfeeding and the use of human milk. Pediatrics 2012; 129: 827-41.
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