Alterações Epiteliais da Córnea Após Descontinuação de Coçar os Olhos em Crianças Atópicas

Autores

  • Tomás Loureiro Hospital Garcia de Orta, Almada, Portugal
  • Sandra Rodrigues-Barros Hospital Garcia de Orta, Almada, Portugal; Hospital CUF Cascais, Lisboa, Portugal; Clínica CUF Almada, Almada, Portugal
  • Ana Rita Carreira Hospital Garcia de Orta, Almada, Portugal
  • Filipe Moraes Hospital Garcia de Orta, Almada, Portugal
  • Pedro Carreira Hospital Garcia de Orta, Almada, Portugal
  • Ana Vide Escada Hospital Garcia de Orta, Almada, Portugal; Clínica CUF Almada, Almada, Portugal; Hospital da Luz Lisboa, Lisboa, Portugal
  • Paul Campos Hospital Garcia de Orta, Almada, Portugal; Hospital da Luz Lisboa, Lisboa, Portugal
  • Inês Machado Hospital Garcia de Orta, Almada, Portugal; Clínica CUF Almada, Almada, Portugal; Hospital CUF TEJO, Lisboa, Portugal
  • Nuno Campos Clínica CUF Almada, Almada, Portugal; Hospital CUF TEJO, Lisboa, Portugal
  • Renato Ambrósio Jr Federal University of the State of Rio de Janeiro, Rio de Janeiro, Brazil

DOI:

https://doi.org/10.48560/rspo.25443

Resumo

Introdução: O nosso objetivo foi fazer a avaliação do efeito de parar de coçar os olhos no perfil epitelial da córnea através de análise com tomografia de coerância ótica do segmento anterior (AS-OCT) em crianças atópicas sem sinais tomográficos de ectasia. 

 

Métodos: Rapazes dextros (idade média 11,2 anos) com hábito de coçar os olhos e tomografia de córnea (Pentacam, Oculus; Wetzlar, Germanh) sem alterações foram incluídos. Foi realizado AS-OCT (Zeiss Cirrus 5000 HD-OCT, Carl Zeiss Meditec, Dublin, CA, USA) na baseline e após 8 semanas de tratamento com cetotifeno tópico sem conservantes (0,25 mg/mL). A espessura epitelial e a espessura total da córnea foram comparadas através de testes não paramétricos emparelhados de Wilcoxon. Um p-value inferior a 0,05 foi considerado estatisticamente significativo. 

 

Resultados: Vinte e cinco rapazes completaram o estudo. Nenhum olho apresentou critérios tomográficos de ectasia (Belin-Ambrosio Deviation Value < 1,22). A espessura epitelial mínima deslocou-se  da região inferotemporal para a região inferotemporal após o tratamento. As diferenças entre a espessura epitelial minima e máxima (-2,8 µm vs -5,2 µm; p<0,01) e entre as regiões nasal e temporal (N-T) (3,1 µm vs 1.4 µm; p<0,01) foram superiores na baseline. A diferença entre as regiões inferior e superior (I-S) (1,1 µm vs 2,7 µm; p<0,01) foi inferior na baseline. 

 

Conclusão: A análise do epitélio da córnea atráves de OCT do segmento anterior revelou um espessamento inferotemporal após tratamento antialérgico e consequente descontinuação do ato de coçar os olhos.  Estes resultados parecem ilustrar o dano deste ato repetido sobre a córnea e salientam a importância de educação da população acerca dos riscos associados ao mesmo.

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Publicado

2021-12-31

Como Citar

Loureiro, T., Rodrigues-Barros, S., Carreira, A. R., Moraes, F., Carreira, P., Vide Escada, A., Campos, P., Machado, I., Campos, N., & Ambrósio Jr, R. (2021). Alterações Epiteliais da Córnea Após Descontinuação de Coçar os Olhos em Crianças Atópicas. Revista Sociedade Portuguesa De Oftalmologia, 45(4), 210–217. https://doi.org/10.48560/rspo.25443

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