Dermatology case


  • Mariana Adrião Department of Pediatrics, Centro Hospitalar de São João
  • João Sarmento Department of Pediatric Cardiology, Centro Hospitalar de São João
  • João Barreira Department of Pediatrics, Centro Hospitalar de São João



Acute, hemorrhagic, infancy, leukocytoclastic vasculitis, purpura, self-limited


Acute hemorrhagic edema of infancy (AHEI) is a small vessels leukocytoclastic vasculitis which typically occurs between 4 and 24 months. It manifests with  palpable purpuric skin lesions and extremities’ edema.
We describe the clinical case of an 18 month-old child brought to the Emergency Room due to purpuric skin lesions distributed throughout his limbs and face with about 12 hours of evolution. Due to the well-being and the normal analytic study, the diagnosis of AHEI was presumed. The progress of the skin lesions was evaluated, with follow-up at 48 hours and seven days after the beginning of the lesions. It was possible to note their evolution and disappearing after three weeks.
AHEI is a self-limited disease, with a benign course, which contrasts with its exuberant purpuric skin lesions. Among its principals differential diagnosis is Henoch-Schonlein Purpura. It is important to recognize this disease, avoiding unnecessary treatments and concerns.


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Dutta A, Ghosh SK. Acute hemorrhagic edema of infancy. Indian Pediatr. 2014 Aug;51(8):677-8.

Hayrullah A. Acute Hemorrhagic Edema of Infancy, Advances in the Etiology, Pathogenesis and Pathology of Vasculitis, 2011, Dr. Luis M Amezcua-Guerra (Ed.), ISBN: 978-953-307-651-5, InTech, DOI: 10.5772/19842.

Dedeoglu F, Kim S. Henoch-Schonlein purpura (immunoglobulin A vasculitis): clinical manifestations and diagnosis. UpToDate 2015



How to Cite

Adrião M, Sarmento J, Barreira J. Dermatology case. REVNEC [Internet]. 2018Oct.17 [cited 2024Mar.1];27(3):203-5. Available from:



Imaging Cases