Maculopapular cutaneous Mastocytosis


  • Crisbety Soares Pinho Department of Pediatrics, Centro Hospitalar e Universitário de Coimbra
  • Inês Barreto Department of Pediatrics, Centro Hospitalar e Universitário de Coimbra
  • Sandra Rebimbas Department of Pediatrics, Centro Hospitalar do Baixo Vouga
  • Sónia Coelho Department of Dermatology, Centro Hospitalar Tondela Viseu



Darier, mastocitose, Pediatrics


Mastocytosis is a rare disorder caused by proliferation and accumulation of mast cells in various tissues, with characteristic symptoms associated with the release of their mediators. Its cutaneous form, usually benign, is the most frequent among children.

The authors report the case of a two-month-old male infant who presented to the Emergency Department with small, tan-to-brown macules and papules distributed mainly on the trunk, which progressively became nodular and bullous, with one month of evolution. Darier´s sign was positive.

The absence of systemic signs and analytic (including serum tryptase level) and echographic changes was consistent with the diagnosis of maculopapular cutaneous mastocytosis, or urticaria pigmentosa, subsequently confirmed by skin biopsy.

Treatment with anti-histaminic therapy and topical immunosuppressant and avoidance of triggering factors led to a positive outcome.


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Author Biography

Crisbety Soares Pinho, Department of Pediatrics, Centro Hospitalar e Universitário de Coimbra

Interna de Pediatria do Hospital Pediátrico de Coimbra


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How to Cite

Pinho CS, Barreto I, Rebimbas S, Coelho S. Maculopapular cutaneous Mastocytosis. REVNEC [Internet]. 2022Apr.4 [cited 2023Jun.3];31(1):68-72. Available from:



Case Reports