Non-celiac gluten sensitivity

Authors

  • Cecilia Bigio Pediatric Intensive Care Unit, Chronic Patients Unit, Hospital Infantil Joana de Gusmão, Secretaria Estadual de Saúde; Department of Pediatrics, Hospital Braga https://orcid.org/0000-0002-7658-1839
  • Mirella Torquato Chronic Patients Unit, Hospital Infantil Joana de Gusmão, Secretaria Estadual de Saúde https://orcid.org/0009-0005-9266-3972
  • Deise Uebel Hospital Universitário Polydoro Ernani São Thiago, EBSERH – UFSC https://orcid.org/0009-0008-1045-4985

DOI:

https://doi.org/10.25753/BirthGrowthMJ.v32.i2.25767

Keywords:

gluten-free diet, gluten-related disorder, non-celiac gluten sensitivity

Abstract

Introduction: Recurrent abdominal pain accounts for up to 5% of consultations in pediatric primary care. An organic cause is found in only 5−10% of children. Non-celiac gluten sensitivity is a condition characterized by intestinal symptoms (including abdominal pain) and extra-intestinal symptoms related to the ingestion of gluten-containing foods in subjects who are not affected by celiac disease or wheat allergy. Treatment is based on a gluten-free diet.
Objectives: The aim of this work was to review relevant studies in Pediatrics on the subject published in recent years, with the purpose of increasing knowledge among pediatric specialists and contributing to raising awareness and maintaining a high index of clinical suspicion of the condition and improving the diagnosis and management of the condition while reducing the use of gluten-free diet without medical advice.
Development: A review was carried out on PubMed and Cochrane databases using terms related to non-celiac gluten sensitivity, and the evidence about gluten, non-celiac gluten sensitivity, biomarkers, epidemiology, and Salerno Criteria (used in the diagnosis of the disease) was assembled and reported.
Conclusion: Establishing the diagnosis of non-celiac gluten sensitivity and other gluten-related disorders is crucial to design measures to facilitate access to gluten-free diets for patients who really need them. More standardized clinical trials in Pediatrics are needed to draw specific conclusions about the disease.

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Published

2023-09-14

How to Cite

1.
Bigio C, Torquato M, Uebel D. Non-celiac gluten sensitivity. REVNEC [Internet]. 2023Sep.14 [cited 2024Jun.20];32(2):108-15. Available from: https://revistas.rcaap.pt/nascercrescer/article/view/25767

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Section

Review Articles