Long-term Biomechanical Properties and Intraocular Pressure in Patients with Keratoconus After Penetrating Keratoplasty and Deep Anterior Lamellar Keratoplasty

Authors

  • Ana Marta Department of Ophthalmology, Centro Hospitalar Universitário do Porto, Oporto, Portugal https://orcid.org/0000-0003-3495-4649
  • Catarina Castro Department of Ophthalmology, Centro Hospitalar Universitário do Porto, Oporto, Portugal
  • Pedro Manuel Baptista Department of Ophthalmology, Centro Hospitalar Universitário do Porto, Oporto, Portugal
  • Nadine Gonçalves Department of Ophthalmology, Centro Hospitalar Universitário do Porto, Oporto, Portugal
  • Miguel Mesquita Neves Department of Ophthalmology, Centro Hospitalar Universitário do Porto, Oporto, Portugal
  • Miguel Gomes Department of Ophthalmology, Centro Hospitalar Universitário do Porto, Oporto, Portugal
  • Luís Oliveira Department of Ophthalmology, Centro Hospitalar Universitário do Porto, Oporto, Portugal

DOI:

https://doi.org/10.48560/rspo.25903

Keywords:

Biomechanical Phenomena, Cornea/physiology, Intraocular Pressure, Keratoconus, Keratoplasty, Penetrating

Abstract

INTRODUCTION: Our aim was to compare long-term biomechanical properties and in- traocular pressure between eyes treated with penetrating keratoplasty (PKP) and deep anterior lamellar keratoplasty (DALK) in patients with keratoconus and healthy patients.

METHODS: Retrospective observational case-control study with corneal biomechanical evaluation by ultra-high-speed Scheimpflug imaging during noncontact tonometry (Corvis ST, OCULUS®). The intraocular pressure (IOP) was assessed with: Goldmann applanation tonometer; noncontact tonometer and biomechanically corrected by the Corvis ST and Pentacam corrected system (Ehlers, Shah, Dresden, and Spoerl correction).

RESULTS: The study included 104 eyes: 18 PKP-treated eyes, 34 DALK-treated eyes, and 52 healthy eyes. The average age at biomechanical assessment was similar between treated and healthy eyes (p=0.980). The mean follow-up time was similar between PKP- and DALK-treated eyes (p=0.273). PKP- and DALK-treated eyes showed significantly softer behaviour in 1st (19/28 and 21/28, respectively) and 2nd (8/11 and 9/11, respectively) generation biomechanical corneal pa-rameters compared to the control group. There was no difference in 1st and 2nd generation biome- chanical corneal parameters between PKP and DALK-treated eyes and between “big bubble” and “manual dissection” DALK techniques. When analysed postoperative IOP measured by different methods, mean values were similar between PKP- and DALK-treated eyes.

CONCLUSION: Neither of the two keratoplasty techniques fully restored corneal biome- chanics to those of healthy corneas. When comparing directly PKP and DALK-treated eyes, there were no significant differences in biomechanical behaviour. Mean postoperative IOPs measured by different methods were similar between PKP and DALK-treated eyes.

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Published

2023-06-29

How to Cite

Marta, A., Castro, C., Baptista, P. M., Gonçalves, N., Mesquita Neves, M., Gomes, M., & Oliveira, L. (2023). Long-term Biomechanical Properties and Intraocular Pressure in Patients with Keratoconus After Penetrating Keratoplasty and Deep Anterior Lamellar Keratoplasty. Revista Sociedade Portuguesa De Oftalmologia, 47(2), 84–93. https://doi.org/10.48560/rspo.25903

Issue

Vol. 47 No. 2 (2023)

Section

Original Article

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