Optic Disc Structural, Vascular and Functional Assessment in Patients with Primary Raynaud’s Phenomenon
DOI:
https://doi.org/10.48560/rspo.26683Keywords:
Low Tension Glaucoma, Optic Disk, Raynaud Disease, Tomography, Optical CoherenceAbstract
INTRODUCTION: Our aim was to assess optic disc structural, vascular and functional parameters in patients with primary Raynaud’s phenomenon (PRP).
METHODS: This study enrolled patients with PRP and healthy age-matched controls.
Subjects underwent evaluation of intraocular pressure (IOP), anterior chamber angle, optic disc structural and vascular parameters (measured by optical coherence tomography) and visual field.
RESULTS: Twenty-four eyes were included in the control group, with a mean age of 44.20 ± 4.67 years, and 20 eyes in the PRP group, with a mean age of 43.00 ± 6.08 years (p=0.20). Inferior and nasal retinal nerve fiber layer (RNFL) thickness was lower in PRP group (104.05 ± 17.64 vs 118.67 ± 12.60μm, p=0.01; 70.05 ± 12.21 vs 79.50 ± 12.70 μm, p=0.04, respectively). Vascular density was lower in PRP group, mostly in the inner ring (15.90 ± 2.10 vs 14.20 ± 0.43 mm-1, p=0.02). No difference was found in functional parameters (p>0.05). No correlation was found between optic disc vascular density and RNFL thickness on multivariate regression analysis (p>0.05).
CONCLUSION: Our findings suggest that PRP may possibly negatively affect the optic nerve, with a reduced vascular density and RNFL thickness.
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