Issues Related to Antipsychotic and Mood Stabilizer Treatment During Pregnancy and Lactation

Authors

  • Patricia Magalhães Centro Hospitalar do Porto
  • Teresa Sá Departamento de Pedopsiquiatria e Saúde Mental da Infância e da Adolescência, Centro Materno Infantil do Norte, Centro Hospitalar Universitário do Porto
  • Filipa Silva Departamento de Pedopsiquiatria e Saúde Mental da Infância e da Adolescência, Centro Materno Infantil do Norte, Centro Hospitalar Universitário do Porto
  • Filipa Caetano Hospital de Magalhães Lemos
  • Vânia Martins Departamento de Pedopsiquiatria e Saúde Mental da Infância e da Adolescência, Centro Materno Infantil do Norte, Centro Hospitalar Universitário do Porto

DOI:

https://doi.org/10.25752/psi.18552

Keywords:

Palavras-Chave: Psicose Esquizofrénica; Perturbação Afetiva Bipolar; Fármacos psicotrópicos; Antipsicóticos; Gravidez; Aleitamento materno

Abstract

Background: Bipolar Disorder (BD) and Schizophrenic Psychosis (SP) are serious psychiatric disorders, which often require chronic treatment using psychotropic drugs, such us antipsychotics and mood stabilizers. These mental illnesses occur in fertile female and the use of these drugs during pregnancy and lactation raises several challenges. These drugs may have adverse effects for child development but there is a greater risk for mother and baby outcomes in not treating these disorders.

Aims: Summarize the actual available data on the risks of using psychotropic drugs during pregancy and lactation periods in women with BP and SP diagnosis.

Methods: The authors performed a PubMed search, including 30 reviews studies and excluding those that not refer to BD and SP.

Results and Conclusions: Due to ethical issues involved in clinical trials and other studies in pregnant women, the risks associated with antenatal exposure to these medications remains poorly studied. However, recent studies have found that some drugs such as lithium, valproate and carbamazepine may adversely affect the development of embryo and fetus.

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Published

2022-09-07

Issue

Vol. 17 No. 1&2 (2019)

Section

Review Articles

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