Obsessive-Compulsive Symptoms in Treatment-Resistant Schizophrenia: Case Report
DOI:
https://doi.org/10.25752/psi.20081Keywords:
Schizophrenia, Obsessive-Compulsive Disorder, Clinical Overlap, ComorbidityAbstract
Background: Poyurovsky proposed the schizo-obsessive subtype in order to delineate a discrete subgroup of patients with schizophrenia with comorbid obsessive-compulsive symptoms, which cause a cumulative effect on functioning and poor prognosis. We aimed to exemplify the clinical challenges of treatment-resistant schizophrenia with obsessive-compulsive symptoms.
Methods: Report a clinical case, evaluation with psychometric measures, and non-systematic literature review.
Results: This work presents the case of a 43-year-old patient, with treatment-resistant schizophrenia, admitted to the Treatment-Resistant Schizophrenia Unit of Coimbra Hospital and University Centre. The positive, negative, and cognitive symptoms of schizophrenia co-occurred with distinct obsessive-compulsive symptoms. Primary obsessive-compulsive symptoms were present since the schizophrenia prodrome. Other obsessive-compulsive symptoms followed the delusional ideas. Clozapine-induced obsessive-compulsive symptoms appeared later.
Conclusions: Accurate diagnosis of obsessive-compulsive symptoms enables their effective treatment.
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