Is There Such a Diagnosis as an Early Onset Unipolar Depression?
DOI:
https://doi.org/10.25752/psi.6033Keywords:
Depression, Unipolar, Bipolar, Early-onset, Kraepelin.Abstract
According to Kraepelin, melancholia was part of manic-depressive psychosis. In the 60s however, other authors (Angst, 1966; Perris, 1966; Winokur, 1967) questioned this concept by considering unipolar depression a clinical entity, separated from bipolar disorders. Using strict bipolar disorders criteria, some prospective studies have shown a diagnosis switch from unipolar to bipolar disorders in up to 50% of the cases (Caryell, 1995; Goldberg, 2001; Angst, 2005). The existence of unipolar depression as a clinical entity is discussed, taking in consideration the “minor” bipolar symptoms that occur during the course of affective disorders.
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