Neuropsychiatric Adverse Effects of HCV or HBV treatment with Interferon-Alpha

Authors

  • Carlota Tomé Serviço de Psiquiatria, Hospital Prof. Doutor Fernando Fonseca, EPE
  • Alice Luís Serviço de Psiquiatria, Hospital Prof. Doutor Fernando Fonseca, EPE

DOI:

https://doi.org/10.25752/psi.6088

Keywords:

Viral hepatitis, interferon-alpha, adverse events, neuropsychiatric symptoms, contraindications

Abstract

The published bibliography about neuropsychiatric adverse events related to the treatment with interferon alpha in patients suffering from viral hepatitis is reviewed. The authors pointed out adverse events such as mood disorders, anxiety disorders, suicide and deliberate self-harm, manic symptoms and psychotic disturbance. The onset of these psychiatric disorders may be a cause for poor, non-compliance or discontinuation with medical treatment. A good response to psychiatric treatment is observed so that it’s many times possible to maintain medical treatment. A multidisciplinary team in order to facilitate early assessment and treatment of this conditions may contribute for a better prognosis of patients with viral hepatitis.

Published

2004-06-01

Issue

Section

Review Articles