Psychiatric Diseases as Systemic Disorders
DOI:
https://doi.org/10.25752/psi.7643Keywords:
Autoimmune Diseases, Autoimmune Encephalitis, Systemic Illness, Psychiatric Manifestations.Abstract
Background: In the past years, there has been a growing body of evidence regarding the pathogenic role of neuroinflammation in psychiatric illness, with consequent conceptual evolution regarding the relationship between psychiatric illness and systemic disease.
Aims: Literature review based on relationship between psychiatric illness and systemic disease.
Methods: Nonsystematic literature review based on selected articles and books deemed relevant by the author.
Results and Conclusions: The role of neuroinflammation in psychiatric illness is well documented in systemic autoimmune diseases associated with psychiatric manifestations, but also in some infectious diseases and cancer. Parallel to this link, neuroimmunological abnormalities occur in classical psychiatric disorders such as depressive and bipolar disorders, obsessive-compulsive disorder and schizophrenia.
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