Psychoimmunology Consultation - A Study on Comorbidity

Authors

  • Mariana Marinho Clínica de Psiquiatria e Saúde Mental do Centro Hospitalar de São João
  • João Marques Serviço de Psiquiatria da Unidade Local de Saúde de Matosinhos
  • Manuel Esteves Clínica de Psiquiatria e Saúde Mental do Centro Hospitalar de São João. Faculdade de Medicina da Universidade do Porto
  • António Roma-Torres Clínica de Psiquiatria e Saúde Mental do Centro Hospitalar de São João
  • Miguel Bragança Clínica de Psiquiatria e Saúde Mental do Centro Hospitalar de São João. Faculdade de Medicina da Universidade do Porto

DOI:

https://doi.org/10.25752/psi.8491

Keywords:

Adaptation/psychological, AIDS, Brain/immunology, Disease progression, HIV infections/immunology, HIV infections/ psychology, HIV seropositivity/immunology, Humans, Mental disorders, Psychiatry, Psychology, Psychoneuroimmunology

Abstract

Introduction: In comparison to the general population, notified  HIV-positive patients have higher prevalence  rates for most mental disorders, with values reaching 30-60%.

Objectives: To characterize the population that is referred to Psychiatry-Psychoimmunology consultation; to explore the possible relationship  between  psychiatric  diagnosis, antiretroviral treatment and HCV co-infection, with sociodemographic and clinical variables.

Methods: We have selected HIV-positive patients referred for the first time to Psychiatry-Psychoimmunology consultation, between January 2012 and July 2015. Information was collected through the clinical process in electronic form. Statistical analy- sis was performed using the statistical analysis  program  Statistical  Package for Social Sciences, version 20.

Results: The sample contained 209 patients, with a median age of 43 years, mostly men, with four years of schooling, single, professionally inactive, infected via heterosexual behavior. However, we found statistically significant differences between sexes for the last three variables. The majority was under antiretroviral treatment, with no significant differences between sexes. In the first consultation, 29.0% and 30.1% had, respectively, substance use and HCV co-infection, with a significant predominance in men. Depressive symptoms and adjustment disorder to the disease constituted, respectively, the referral reason and the most common psychiatric diagnosis, in both sexes. More than half had psychiatric history. HCV co-infection showed a statistical significant correlation between variables like sex, occupational status, infection transmission route,  psychiatric  history  and  use  of  alcohol and/or illicit drugs. The same was true between the psychiatric diagnosis and some variables like infection notification  time, alcohol and/or drugs and HCV co-infection.

Conclusions: During the course of infection, these patients often face multiple stress- ors that can make them more vulnerable to mental illness. The availability of an effective psychiatric care is therefore crucial, and it is necessary to increase the future research in this area."

Published

2017-03-15

Issue

Section

Original Articles