18F-FDG uptake in breast tissue related to breastfeeding

Abstract

A young patient underwent PET-CT with ¹⁸F-FDG, which showed intense uptake of radiopharmaceutical in breast tissue related to breastfeeding. After stopping breastfeeding, the patient was again studied with PET-CT, with no evidence of breast uptake of ¹⁸F-FDG.

As described in the literature, this case demonstrates intracellular FDG uptake in active glandular tissue, which remains even immediately after breastfeeding, suggesting that little ¹⁸F-FDG is excreted in milk.