Intrapancreatic Extramedullary Plasmacytoma Mimicking Primary Pancreatic Neoplasia

Abstract

Extramedullary plasmacytomas are uncommon plasma cell tumors that present outside the bone marrow. The most common site where they have been found is the upper respiratory tract, being pancreatic involvement rare. There are no specific imaging findings and usually the definite diagnosis requires biopsy. They have a good response to radiation if they are localized; when they occur as part of multiple myeloma, their outcome is dismal.

In this report, we describe a case of a pancreatic plasmacytoma in a male patient with underlying multiple myeloma in progression and history of distal pancreatectomy due to a neuroendocrine tumor, focusing on imaging findings.