Anaphylaxis to patent blue dye: a case report
DOI:
https://doi.org/10.25751/rspa.4077Keywords:
Anaphylaxis/chemically induced, Breast Neoplasms, Coloring Agents, Rosaniline Dyes/adverse effectsAbstract
Patent blue dye is one of the synthetic dyes used in the identification of sentinel lymph nodes in patients with breast cancer. The administration of dyes is becoming increasingly frequent in surgeries and under general anesthesia the early signs of anaphylaxis may be undetected.
A 56 year-old woman with breast cancer was submitted to mastectomy under general anesthesia. After the anesthetic induction and administration of the dye, the patient exhibited facial and limb rash and hypotension. Anaphylaxis was suspected, so the patient was treated as per protocol, with partial recovery, and the surgery was postponed.
Given the oncological context, surgery took place a few days later; some drugs were altered, patent blue dye was avoided and an allergic reaction prevention protocol was established. The surgery was performed without complications; afterwards allergy to patent blue dye was confirmed through prick tests.
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