• Catarina Matos Department of Pediatrics, Centro Hospitalar Tâmega e Sousa
  • Susana Lira Department of Pediatrics, Centro Hospitalar Tâmega e Sousa
  • Carla Brandão Department of Pediatrics, Centro Hospitalar Tâmega e Sousa
  • Leonilde Machado Department of Pediatrics, Centro Hospitalar Tâmega e Sousa



Benign entity, afebrile seizures, children, acute gastroenteritis, rotavirus


Introduction: Benign afebrile convulsions associated with mild acute gastroenteritis are seizures that occur in apyrexia, accompanying acute gastroenteritis without dehydration or electrolyte imbalance.
Case report: We describe the case of a 15 months old child, with the occurrence of three seizures within a few hours associated with mild acute gastroenteritis, with no fever or clinical signs of dehydration. Laboratory tests revealed no hydroelectrolytic changes. Rotavirus antigen in stool was positive. EEG and brain CT showed no abnormalities. No speciÞ c treatment was started, and outcome was good, with no further seizures in less than 24 hours and improvement of gastrointestinal symptoms in four days. There was no recurrence of seizures and subsequent psychomotor development was normal.
Conclusion: The authors aim to highlight the importance of recognizing this entity and its benign nature, being self-limited and with an excellent outcome, avoiding an extensive investigations and long-term therapy with antiepilepyic drugs.


Download data is not yet available.


E, Chiarelli F.

Afebrile benign convulsions with mild gastroenteritis: a new

entity? Acta Neurol. Scand 2009;120:73 -9.

Dinis MJ, Teles A, Chorão R, Carrilho I, Santos M. Convulsões

apiréticas benignas associadas a gastroenterite aguda ligeira

(CABAGAL) na criança. Saúde Infantil 2009; 31:125 -8.

Narchi H. Benign afebrile cluster convulsions with gastroenteritis:

an observational study. BMC Pediatrics 2004;4:2.

Chen S, Tsai C, Lai M, Chen C, Lin K, Lin T, et al. Norovirus

infection as a cause of diarrhea -associated benign infantile

seizures. Clin Infect Dis 2009;48:849 -55.

Caraballo R, Ganez L, De los Santos C, Espeche A, Cersósimo

R, Fejerman N. Benign infantile seizures with gastroenteritis:

Study of 22 patients. Seizure 2009;18:686 -9.

Morooka K. Convulsions and mild diarrhea. Shonika Rinsho

;23:131 -7.

Verrotti A, Nanni G, Agostinelli S, Parisi P, Copovilla G,

Beccaria F, et al. Benign convulsions associated with mild

gastroenteritis: A multicenter clinical study. Epilepsy Res

;93:107 -14.

Saadelin IY. Electroclinical features of benign infantile seizures

with mild gastroenteritis. Epileptic Disord 2011;13:8 -17.

Cusmai R, Jocic -Jakubi B, Cantonetti L, Japaridze N, Vigevano

F. Convulsions associated with gastroenteritis in

spectrum of benign focal epilepsies in infancy: 30 cases including

four cases with ictal EEG recording. Epileptic Disord

;12:255 -61.

Patteau G, Stheneur C, Chevallier B, Parez N. Convulsions

non fébriles bénignes associées à une gastro -entérite aigue à

rotavirus chez l´enfant. Arch Pediatr 2010;17: 1527 -30.

Martí I, Cilla G, Gomáriz M, Eizaguirre J, Gárcia- Pardos C,

Pérez -Yarza EG. Rotavirus y crisis convulsivas. Una associación

poco frecuente aunque bien deÞ nida. An Pediatr (Barc)

;73:70 -3.



How to Cite

Matos C, Lira S, Brandão C, Machado L. AFEBRILE BENIGN CONVULSIONS ASSOCIATED WITH MILD GASTROENTERITIS. REVNEC [Internet]. 2017Aug.22 [cited 2024Jun.24];22(1):30-2. Available from:



Case Reports

Most read articles by the same author(s)