COVID-19-induced rhabdomyolysis in an adolescent: A rare presentation




COVID-19, muscle, myositis, rhabdomyolysis


Viral infections are a well-known cause of myositis. The clinical presentation may vary from mild myalgia to severe muscle injury. Coronavirus disease 2019 (COVID-19), a viral respiratory disease caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), can be a cause of myositis and of rhabdomyolysis, a rare and severe complication.
A previously healthy 11-year-old female adolescent with COVID-19 presented to the Emergency Department with lower limb pain and inability to walk. The initial laboratory study revealed a marked elevation of muscular enzymes, particularly creatine kinase (13046 UI/L; reference value 149 UI/L). Urine dipstick test reacted positively for hemoglobinuria. The patient started treatment with aggressive intravenous hydration, with progressive clinical and analytical improvement.
Musculoskeletal symptoms associated with COVID-19 are a frequent complaint, with potentially severe complications, such as rhabdomyolysis. A proper and timely diagnosis can prevent further clinical deterioration and enable adequate treatment and follow-up.


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How to Cite

Calejo R, Queirós J, Brandão C, Barroso F, Machado L. COVID-19-induced rhabdomyolysis in an adolescent: A rare presentation. REVNEC [Internet]. 2022Oct.19 [cited 2024Mar.2];31(3):317-20. Available from:

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