Current view of vitamin D in pregnant women: a review


  • Kadija Rahal Chrisostomo Setor de Ciência da Sáude, Universidade Federal do Paraná
  • Jaime Kulak Junior Setor de Ciência da Sáude, Universidade Federal do Paraná
  • Almir Urbanetz Setor de Ciência da Sáude, Universidade Federal do Paraná
  • Eduardo Rahal Chrisostomo Faculdade Evangélica Mackenzie do Paraná
  • Renato Mitsunori Nisihara Setor de Ciência da Sáude, Universidade Federal do Paraná; Faculdade Evangélica Mackenzie do Paraná; Faculdade Positivo Londrina, Universidade Positivo



deficiency, pregnancy, insufficiency, vitamin D


Hypovitaminosis D is a global health problem that affects all age groups. Pregnant women are considered a high-risk group and the condition has potentially associated maternal and fetal complications. The goal of the present review is to analyze the magnitude and consequences of hypovitaminosis D in pregnant women and the safety of vitamin D supplementation. Prevalence of hypovitaminosis D during pregnancy is very high, even in sunny countries. Maternal vitamin D deficiency has been associated with increased risk of specific hypertensive disease of pregnancy, bacterial vaginosis, prematurity, gestational diabetes mellitus, osteomalacia, and muscle weakness. It has also been linked to prematurity, low birth weight, and fetal infectious complications.
Due to potential maternal and fetal complications, it is extremely important to achieve adequate vitamin D levels prior to pregnancy. During pregnancy, it would be prudent to monitor serum vitamin D levels and implement preventive measures to reduce maternal and fetal morbidity.
No consensus exists in the medical literature regarding vitamin D supplementation in pregnant women.


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How to Cite

Chrisostomo KR, Kulak Junior J, Urbanetz A, Chrisostomo ER, Nisihara RM. Current view of vitamin D in pregnant women: a review. REVNEC [Internet]. 2019Jul.18 [cited 2023Jun.1];28(2):77-83. Available from:



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