Difficult management of pediatric acute Q fever


  • Rafael Costa Figueiredo Department of Pediatrics, Centro Materno-Infantil do Norte, Centro Hospitalar Universitário do Porto
  • Diana R. Monteiro Department of Pediatrics, Centro Hospitalar de Entre Douro e Vouga
  • Ana Isabel Rebelo Department of Pediatrics, Centro Hospitalar de Entre Douro e Vouga
  • Ana Azevedo Department of Pediatrics, Centro Hospitalar de Entre Douro e Vouga
  • Sara Freitas de Oliveira Department of Pediatrics, Centro Hospitalar de Entre Douro e Vouga
  • Susana Tavares Department of Pediatrics, Centro Hospitalar de Entre Douro e Vouga


acute Q fever, Acute Q fever; Doxycycline; Paediatric Q fever., pediatric Q fever


Introduction: Q fever, a zoonosis caused by Coxiella burnetti, is relatively rare in the pediatric population. The disease is often asymptomatic or with mild clinical presentation in children.

Case report: A four-year-old boy with persistent fever, severe anemia, and positive IgM for Coxiella burnetti was treated with trimethoprim-sulfamethoxazole and azithromycin, with no improvement. After polymerase chain reaction confirmation, he completed 14 days of doxycycline, with good response. After eleven months, the child remains asymptomatic.

Discussion: Despite having a usually mild presentation, the severe clinical progression and lack of response to initial antibiotic therapy in this case prompt the use of doxycycline, a non-consensual drug in younger ages, with good results. New recommendations endorse the use of this drug for short periods at any age.


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How to Cite

Figueiredo RC, Monteiro DR, Rebelo AI, Azevedo A, de Oliveira SF, Tavares S. Difficult management of pediatric acute Q fever. REVNEC [Internet]. 2021Sep.30 [cited 2024Jul.23];30(3):179-82. Available from: https://revistas.rcaap.pt/nascercrescer/article/view/17089



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