Polycythemia vera: a case report

  • Joana Macedo Pediatric Service of Centro Hospitalar do Alto Ave
  • Emília Costa Pediatric Hematology Unit, Centro Hospitalar do Porto
  • José Barbot Pediatric Hematology Unit, Centro Hospitalar do Porto
  • Cláudia Neto Pediatric Service of Centro Hospitalar do Alto Ave
Keywords: Adolescence, Polycythemia vera, Thrombosis, Thrombocytosis

Abstract

Polycythemia vera (PV) is a myeloproliferative disturbance of haematopoietic cells characterized by abnormal and overstated production of erythrocytes, leukocytes and platelets. Other disease features include splenomegaly, thrombohemorrhagic complications, vasomotor disturbances, pruritus and a small risk of disease progression into acute myeloid leukemia or myelofibrosis. Thrombosis is the presenting symptom in 20% of patients with PV. It is a rare disease with an incidence of 2.3/100.000 people per year, and is even more uncommon in children and adolescents. We present a case report of a fourteen-year-old years old adolescent with clinical and laboratorial findings suggestive of polycythemia vera. Treatment with alpha-interferon was initiated. Erythrocyte and platelet count are now in the normal range. The authors make, in the context of this case report, a brief review of the criteria for the differential diagnosis of reactive thrombocytosis and myeloproliferative diseases, manifestations and treatment options.

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Published
2015-06-15
How to Cite
Macedo, J., Costa, E., Barbot, J., & Neto, C. (2015). Polycythemia vera: a case report. NASCER E CRESCER - BIRTH AND GROWTH MEDICAL JOURNAL, 24(2), 83-87. https://doi.org/10.25753/BirthGrowthMJ.v24.i2.8565
Section
Case Reports