Plasmapheresis in acute disseminated encephalomyelitis associated with anti-MOG antibodies – Two clinical cases

Authors

  • Joana Soares Department of Neonatology and Pediatrics, Centro Hospitalar do Tâmega e Sousa
  • Rafael Figueiredo Department of Pediatrics, Centro Materno-Infantil do Norte, Centro Hospitalar Universitário do Porto https://orcid.org/0000-0002-4456-2975
  • Eduarda Pinto Department of Neuroradiology, Centro Hospitalar Universitário do Porto
  • Ana Lúcia Cardoso Department of Neonatal and Pediatric Intensive Care, Centro Materno-Infantil do Norte, Centro Hospitalar Universitário do Porto https://orcid.org/0000-0002-1575-5006
  • Alzira Sarmento Department of Neonatal and Pediatric Intensive Care, Centro Materno-Infantil do Norte, Centro Hospitalar Universitário do Porto https://orcid.org/0000-0002-5397-0057
  • Maria Sameiro Faria Pediatric Nephrology Unit, Department of Pediatrics, Centro Materno-Infantil do Norte, Centro Hospitalar Universitário do Porto
  • Sónia Figueiroa Neuropediatris Unit, Department of Pediatrics, Centro Materno-Infantil do Norte, Centro Hospitalar Universitário do Porto
  • Paula Ferreira Department of Neonatal and Pediatric Intensive Care, Centro Materno-Infantil do Norte, Centro Hospitalar Universitário do Porto https://orcid.org/0000-0001-8184-5870

DOI:

https://doi.org/10.25753/BirthGrowthMJ.v31.i2.25273

Keywords:

acute disseminated encephalomyelitis, demyelinating diseases, anti-MOG antibody, neurologic signs

Abstract

Acute disseminated encephalomyelitis (ADEM) is an acute demyelinating disorder of the central nervous system. ADEM should be suspected when a patient develops multifocal neurologic abnormalities with encephalopathy, especially if occurring after a viral infection or immunization. In this study, the authors describe two cases of ADEM with positive anti-myelin oligodendrocyte glycoprotein (MOG) antibodies requiring hospitalization in a Pediatric Intensive Care Unit and plasmapheresis treatment.

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References

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Published

2022-06-30

How to Cite

1.
Soares J, Figueiredo R, Pinto E, Cardoso AL, Sarmento A, Sameiro Faria M, Figueiroa S, Ferreira P. Plasmapheresis in acute disseminated encephalomyelitis associated with anti-MOG antibodies – Two clinical cases. REVNEC [Internet]. 2022Jun.30 [cited 2025Jan.24];31(2):156-61. Available from: https://revistas.rcaap.pt/nascercrescer/article/view/25273

Issue

Vol. 31 No. 2 (2022)

Section

Case Reports

License

Copyright (c) 2022 Joana Soares, Rafael Figueiredo, Eduarda Pinto, Ana Lúcia Cardoso, Alzira Sarmento, Maria Sameiro Faria, Sónia Figueiroa, Paula Ferreira

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