Mucormicose rino-orbito-cerebral num doente oncológico pediátrico

Autores

  • Maria Eduarda Couto Serviço de Onco-Hematologia, Instituto Português de Oncologia do Porto Francisco Gentil. https://orcid.org/0000-0003-2092-0325
  • Tereza Oliva Serviço de Pediatria, Instituto Português de Oncologia do Porto Francisco Gentil
  • Pedro Alberto Serviço de Neurocirurgia, Centro Hospitalar e Universitário São João
  • Ana Lebre Serviço de Doenças Infeciosas, Instituto Português de Oncologia do Porto
  • Armando Pinto Serviço de Pediatria, Instituto Português de Oncologia do Porto Francisco Gentil
  • Ana Maia Ferreira Serviço de Pediatria, Instituto Português de Oncologia do Porto Francisco Gentil

DOI:

https://doi.org/10.25753/BirthGrowthMJ.v30.i4.19758

Palavras-chave:

antifúngico, encefalite, mucormicose, osteomielite, Rhizopus sp

Resumo

Objetivo: As infeções por mucormicose associam-se a elevada mortalidade em doentes imunocomprometidos. Os autores descrevem um raro caso clínico de tratamento com sucesso da condição.

Descrição do caso: Um rapaz de 14 anos de idade com linfoma linfoblástico agudo em remissão foi diagnosticado com pansinusite, osteomielite cerebral e encefalite com abcesso causada por Rhizopus sp. Foi realizada drenagem neurocirúrgica, cirurgia endoscópica naso-sinusal e enucleação do olho esquerdo. O doente iniciou tratamento com anfotericina B lipossómica e posaconazol (posteriormente substituído por isavuconazol). No entanto, o desenvolvimento de complicações (herniação do lobo frontal esquerdo e fístula de líquido cefalorraquídeano) exigiu reintervenção cirúrgica. Quatro meses depois, foi reiniciada quimioterapia.

Comentários: Este é um caso clínico raro, no qual cirurgia precoce e agressiva, antifúngicos adequados e abordagem por uma equipa multidisciplinar foram determinantes para o sucesso alcançado.

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Publicado

2021-12-27

Como Citar

1.
Couto ME, Oliva T, Alberto P, Lebre A, Pinto A, Maia Ferreira A. Mucormicose rino-orbito-cerebral num doente oncológico pediátrico. REVNEC [Internet]. 27 de Dezembro de 2021 [citado 2 de Julho de 2024];30(4):241-5. Disponível em: https://revistas.rcaap.pt/nascercrescer/article/view/19758

Edição

Vol. 30 N.º 4 (2021)

Secção

Casos Clínicos

Licença

Direitos de Autor (c) 2021 Maria Eduarda Couto, Tereza Oliva, Pedro Alberto, Ana Lebre, Armando Pinto, Ana Maia Ferreira

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Este trabalho encontra-se publicado com a Creative Commons Atribuição-NãoComercial 4.0.

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