Multiple Myeloma Involvement of the Pancreas: A Case Report ofPancreatic Extramedullary Plasmacytomas Causing Obstructive Jaundice

Abstract

Extramedullary plasmacytomas are rare tumors that can occur either as primary lesions (primary tumors) or as a manifestation of multiple myeloma (secondary tumors). Pancreatic involvement by myeloma is very rare (less than 0,1% of pancreatic masses).

Radiological findings are not specific. On CT, the most typical finding is the presence of a focal multilobulated mass with homogeneous contrast enhancement. 

This is a case report of a 74-year-old woman with a previous history of stage III multiple myeloma presented to the emergency department with complaints of abdominal discomfort and painless jaundice. Ultrasound and CT scan of the abdomen were performed and revealed a large mass in the topography of the pancreatic head which, after histological analysis, revealed that it was a pancreatic plasmacytoma.

The purposes of this article are to present a rare case of pancreatic extramedullary plasmacytomas, describe its epidemiology and clinical features, as well as illustrate its imaging findings.