Pollen-food syndrome in the adolescent


  • Joana Sofia Pita Department of Allergy and Clinical Immunology. Hospital Dona Estefânia. Centro Hospitalar Universitário de Lisboa Central
  • Maria Luís Marques Department of Allergy and Clinical Immunology. Centro Hospitalar Universitário do Porto
  • Moisés Labrador-Horrillo Allergy Section. Hospital Universitario Vall d’Hebron
  • Helena Falcão Department of Allergy and Clinical Immunology. Centro Hospitalar Universitário do Porto
  • Leonor Cunha Department of Allergy and Clinical Immunology. Centro Hospitalar Universitário do Porto




allergy, pollen-food-syndrome, profilin


Pollen-food syndrome (PFS) is characterized by allergic symptoms elicited by the ingestion of raw fruits or vegetables in patients with seasonal allergic rhinitis/rhinoconjunctivitis. The estimated prevalence of PFS in patients with pollen allergy is 50–70%. Typically, PFS-induced symptoms are restricted to the oral cavity (oral allergy syndrome – OAS). The authors present the case of a female adolescent with grass pollen allergic rhinitis treated with oral immunotherapy for four years and four months, who developed OAS to fresh fruits and walnuts. Diagnostic workup showed sensitization to several allergens, particularly to profilin, which seems to be responsible for PFS. The patient remains asymptomatic with fresh fruits and walnut avoidance, currently tolerating cooked apple, without symptoms.


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How to Cite

Pita, J. S., Marques, M. L., Labrador-Horrillo, M., Falcão, H., & Cunha, L. (2019). Pollen-food syndrome in the adolescent. NASCER E CRESCER - BIRTH AND GROWTH MEDICAL JOURNAL, 28(3), 145–149. https://doi.org/10.25753/BirthGrowthMJ.v28.i3.15730



Case Reports