Hypersensitivity vasculitis after treatment with methylphenidate - case report


  • Mário Correia de Sá Pediatric Service of Centro Hospitalar Vila Nova de Gaia / Espinho
  • Carolina Faria Hospital Pediátrico – Centro Hospitalar e Universitário de Coimbra
  • Marta Alves Hospital Pediátrico – Centro Hospitalar e Universitário de Coimbra
  • Liliana Macedo Pediatric Service of Centro Hospitalar do Alto Ave
  • Sónia Carvalho Pediatric Service of Centro Hospitalar do Médio Ave




hypersensitivity, methylphenidate, vasculitis


Introduction: Hypersensitivity vasculitis is the small blood vessels’ inflammation secondary to the formation and endothelial deposition of immune complexes.

Case Report: We describe a case of a 15 year-old female, recently medicated with methylphenidate for attention deficit hyperactivity disorder who presented recurrent episodes of feet pain and purpuric lesions on the toes. The lesions’ histopathological study showed findings consistent with lymphocytic vasculitis.

Discussion: The clinical and histopathological findings associated with the temporal relationship between the initiation of treatment with methylphenidate and the onset of symptoms and clinical resolution after discontinuation of the drug permitted the diagnosis of hypersensitivity vasculitis.


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How to Cite

de Sá MC, Faria C, Alves M, Macedo L, Carvalho S. Hypersensitivity vasculitis after treatment with methylphenidate - case report. REVNEC [Internet]. 2015Jun.15 [cited 2024Jul.20];24(2):79-82. Available from: https://revistas.rcaap.pt/nascercrescer/article/view/8564



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