HEALTHCARE -ASSOCIATED INFECTIONS IN A NICU: EVALUATION OF THE EFFECTIVENESS OF IMPLEMENTED PREVENTION STRATEGIES

  • Liliana Pinho Serviço de Neonatologia do Centro Hospitalar do Porto
  • Joana Pinto Serviço de Neonatologia do Centro Hospitalar do Porto
  • Ana Cristina Braga Serviço de Neonatologia do Centro Hospitalar do Porto
  • Sónia Gouveia Instituto de Engenharia Electrónica e Telemática de Aveiro da Universidade de Aveiro; Centro I&D em Matemática e Aplicações da Universidade de Aveiro
  • Luísa Matos Serviço de Neonatologia do Centro Hospitalar do Porto
  • José Pombeiro Serviço de Neonatologia do Centro Hospitalar do Porto
  • Alexandra Almeida Serviço de Neonatologia do Centro Hospitalar do Porto
Keywords: Central venous catheter, healthcare-associated infections, neonatal intensive care unit, prevention, sepsis

Abstract

Introduction: Neonates admitted to Neonatal Intensive Care Units (NICU) have a substantial risk for healthcare-associated infections (HAI). A high incidence of HAI was found in Maternidade Júlio Dinis (MJD) NICU and led to changes in daily clinical practice.

Objectives: To evaluate the effectiveness of new strategies for prevention of infection implemented in the NICU of MJD.

Methods: We conducted a prospective study that included all infants admitted to the NICU of MJD during the 16 months before (group 1) and 16 months after (group 2) the protocol change, comparing the rates of infection in these two time periods.

Results: 528 infants were included in group 1 and 593 in group 2, with no statistical evidence of different characteristics between them (weight, gestational age, CVC utilization rate, duration of parenteral nutrition and invasive ventilation). Overall mean infection indices decreased between the two periods: incidence -density of infection – sepsis, pneumonia, necrotizing enterocolitis and meningitis – (10,0 vs. 6,3; p=0,0007), incidence- -density of clinical plus laboratory -confirmed sepsis (9,6 vs. 5,9; p=0,0007), incidence -density of laboratory -confirmed sepsis (6,8 vs. 4,6; p=0,015), incidence rate of central vascular catheter (CVC) -associated sepsis (30,3 vs. 22,4; p=0,021) and coagulase- -negative Staphylococcus isolation rate (85,7% vs. 71,1%; p=0,041). Although incidence rate of laboratory -confirmed CVC- -associated sepsis decreased (22 vs. 19), the difference was not significant. Similar tendencies were observed considering very low birth weight neonates.

Conclusions: This study demonstrated that an evidence- -based intervention was effective, resulting in a decrease of 37% of the HAI in the NICU of MJD.

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Published
2016-09-05
How to Cite
Pinho, L., Pinto, J., Braga, A. C., Gouveia, S., Matos, L., Pombeiro, J., & Almeida, A. (2016). HEALTHCARE -ASSOCIATED INFECTIONS IN A NICU: EVALUATION OF THE EFFECTIVENESS OF IMPLEMENTED PREVENTION STRATEGIES. NASCER E CRESCER - BIRTH AND GROWTH MEDICAL JOURNAL, 22(4), 210-215. https://doi.org/10.25753/BirthGrowthMJ.v22.i4.9751
Section
Original Articles