Dermatology clinical case

Authors

  • Vera Gonçalves Department of Pediatrics, Unidade Local de Saúde do Alto Minho
  • André Costa e Silva Department of Pediatrics, Unidade Local de Saúde do Alto Minho
  • André Azevedo Department of Pediatrics, Unidade Local de Saúde do Alto Minho https://orcid.org/0000-0001-8530-1803
  • Isabel Martinho Department of Pediatrics, Unidade Local de Saúde do Alto Minho
  • Sandrina Martins Department of Pediatrics, Unidade Local de Saúde do Alto Minho https://orcid.org/0000-0002-8853-9099
  • Vera Teixeira Department of Dermatology, Unidade Local de Saúde do Alto Minho https://orcid.org/0000-0002-7708-0753

DOI:

https://doi.org/10.25753/BirthGrowthMJ.v32.i4.26261

Keywords:

erythema multiforme, mycoplasma pneumoniae, mycoplasma pneumoniae-induced rash and mucositis, Stevens-Johnson syndrome, toxic epidermal necrolysis

Abstract

The authors report the case of an eight-year-old boy who presented to the Pediatric Emergency Department for severe oral mucositis, fever, purulent conjunctivitis, and skin rash. The diagnosis of Mycoplasma pneumoniae-induced rash and mucositis (MIRM) was established. Extrapulmonary complications of Mycoplasma pneumoniae infections are increasingly recognized. Over the years, patients with mucocutaneous manifestations have been misdiagnosed with erythema multiforme spectrum disease. In 2015, MIRM was proposed as a distinct clinical entity with unique pathophysiology, clinical manifestations, and prognosis.

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References

Waites KB, Talkington DF. Mycoplasma pneumoniae and its role as a human pathogen. Clin Microbiol Rev. 2004;17(4):697-728.

Canavan TN, Mathes EF, Frieden I, Shinkai K. Mycoplasma pneumoniae-induced rash and mucositis as a syndrome distinct from Stevens-Johnson syndrome and erythema multiforme: a systematic review. J Am Acad Dermatol. 2015;72(2):239-45.

Meyer Sauteur PM, Theiler M, Buettcher M, Seiler M, Weibel L, Berger C. Frequency and Clinical Presentation of Mucocutaneous Disease Due to Mycoplasma pneumoniae Infection in Children With Community-Acquired Pneumonia. JAMA Dermatol. 2019;156(2):144-50.

Shah PR, Williams AM, Pihlblad MS, Nischal KK. Ophthalmic Manifestations of Mycoplasma-Induced Rash and Mucositis. Cornea. 2019;38(10):1305-8.

Brazel D, Kulp B, Bautista G, Bonwit A. Rash and Mucositis Associated With Mycoplasma pneumoniae and Chlamydophila pneumoniae: A Recurrence of MIRM? J Pediatric Infect Dis Soc. 2020.

Martínez-Pérez M, Imbernón-Moya A, Lobato-Berezo A, Churruca-Grijelmo M. Mycoplasma pneumoniae-Induced Mucocutaneous Rash: A New Syndrome Distinct from Erythema Multiforme? Report of a New Case and Review of the Literature. Actas Dermosifiliogr. 2016;107(7):e47-51.

Santos RP, Silva M, Vieira AP, Brito C. Mycoplasma pneumoniae-induced rash and mucositis: a recently described entity. BMJ Case Rep. 2017;2017.

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Published

2024-01-23

How to Cite

1.
Gonçalves V, Costa e Silva A, Azevedo A, Martinho I, Martins S, Teixeira V. Dermatology clinical case. REVNEC [Internet]. 2024Jan.23 [cited 2024Jul.19];32(4):323-5. Available from: https://revistas.rcaap.pt/nascercrescer/article/view/26261

Issue

Vol. 32 No. 4 (2023)

Section

Imaging Cases

License

Copyright (c) 2024 Vera Gonçalves, André Costa e Silva, André Azevedo, Isabel Martinho, Sandrina Martins, Vera Teixeira

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This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

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