DELAYED PUBERTY: A LATE DIAGNOSIS
DOI:
https://doi.org/10.25753/BirthGrowthMJ.v26.i1.11804Keywords:
Failure to thrive, Crohn’s disease, inflammatory bowel disease, pubertal delayAbstract
Background: Pubertal delay is a common condition in the Endocrinology clinic. Many diseases can underlie this phenomenon, being inflammatory bowel disease, namely Crohn’s disease, one of the most commonly related chronic diseases.
Case report: Sixteen-years-old female adolescent, with no previous medical history, was referred to the Pediatric clinic because of pubertal delay with primary amenorrhea and failure to thrive. She had initially no digestive symptoms. She subsequently developed gastrointestinal complaints. Laboratorial, endoscopic and radiological studies that allowed the diagnosis of moderate to severe Crohn’s disease.
Discussion/Conclusion: We aimed to aware Crohn’s disease as one of the causes of pubertal and growth delay, highlighting the need for early diagnosis and therapy, in order to reach a favorable pubertal development.
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References
Bordini B, Rosenfield RL. Normal pubertal development: part I: the endocrine basis of puberty. Pediatrics in review 2011; 32: 223-9.
Kaplowitz PB. Delayed puberty. Pediatrics in review 2010; 31: 189-95.
Cañete Estrada R, Mata Rodrígues C, Aguilar Quintero M. Retraso puberal. Hipogonadismos. Protoc diagn ter pediatr 2011; 1: 205-17.
Crowley WF, Pitteloud Nelly. Diagnosis and treatment of delayed of puberty. 2015; http://www.uptodate.com/online.
Ballinger AB, Savage MO, Sanderson IR. Delayed puberty associated with bowel disease. Pediatr Res 2003; 53:205-10.
Hyams JS. Inflammatory bowel disease. Pediatrics in review 2005; 26:314-20.
Dattani MT, Tziaferi V, Hindmarsh PC. Brook’s Clinical Pediatric Endocrinology. 6th edition. Edited by C. Brook, P. Clayton, R. Brown, 2009: 213-34.
Ruemmele FM, Veres G, Kolho KL, Griffiths A., Levine A, Escher JC, et al. Consensus guidelines of ECCO/ESPGHAN on the medical management of pediatric Crohn’s disease. Journal of Crohn’s and Colitis 2014;8:1179-207.
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