Pregnancy and Thrombophilic Polymorphisms in Paracentral Acute Middle Maculopathy: A Case Report
DOI:
https://doi.org/10.48560/rspo.34130Keywords:
Polymorphism, Genetic, Pregnancy, Retinal Diseases, Retinal Vessels, Thrombophilia, Tomography, Optical CoherenceAbstract
We describe a case of a 34-year-old healthy woman in her first trimester of pregnancy presented with painless acute vision loss in the left eye. Fundus examination revealed a paracentral focal area of retinal whitening that appeared on optical coherence tomography (OCT) as an inner who retina hyperreflectivity and on OCT angiography a severe attenuation of the deep capillary plexus, compatible with paracentral acute middle maculopathy (PAMM). Genetic testing found heterozygous PAI-1 4G/5G and MTHFR (A1298C) mutations, therefore she started antiplatelet therapy. This report highlights that PAMM should be one of the possible diagnoses of acute visual disturbances in pregnancy even in otherwise healthy women.Downloads
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