SCABIES – PRACTICAL RECOMMENDATIONS FOR DIAGNOSIS AND TREATMENT

  • Mónica Tavares Pediatric Department of Centro Hospitalar do Porto
  • Manuela Selores Dermatology Department of Centro Hospitalar do Porto
Keywords: Diagnosis, scabies, sulfur, treatment.

Abstract

Introduction: Scabies is an infection caused by the parasite Sarcoptes scabiei var. hoministhat gains significance due to the morbidity associated with intense itching, high infectivity, frequent outbreaks and persistence of symptoms for many days even after complete eradication.

Objectives: Approach to pathophysiology, differential diagnosis and treatment options in children.

Development: In pediatrics the differential diagnosis of escabiosis with other very common diseases in this age group is sometimes diffi cult. The lack of studies regarding effi cacy and safety of the various available drugs in children makes it diffi cult to drawn recommendations. Scabies treatment is based more on personal experience, local availability and cost than on medical evidence.

Conclusions: This article aims to summarize the pathogenesis of infection by Sarcoptes scabiei var. hominis in children focusing special attention on symptoms and treatment. Although there are no randomized controlled trials with sulfur precipitated in scabies treatment to prove its effi cacy and safety, it seems to be one of the most recommended drugs in this age group.

References

Karthikeyan K. Scabies in children. Arch Dis Child Educ Pract

Ed 2007; 92:ep65 -9.

Chosidow O. Clinical practices. Scabies. N Engl J Med 2006;

:1718 -27.

Esteves JA, Baptista AP, Rodrigo EG, Gomes MA. Dermatologia.

ª edição. Fundação Calouste Gulbenkian, 2005:

-49.

Wolf R, Davidovici B. Treatment of scabies and pediculosis:

facts and controversies. Clin Dermatol 2010; 28:511 -8.

Leone PA. Scabies and pediculosis pubis: an update of treatment

regimens and general review. Clin Infect Dis 2007;

:S153 -9.

Walton SF, Currie BJ. Problems in diagnosing scabies, a global

disease in human and animal populations. Clin Microbiol

Rev 2007; 20:268 -79.

Chosidow O. Scabies and pediculosis. Lancet 2000; 355:819-

-26.

Eichenfi eld L, Frieden I, Esterly N. Neonatal Dermatology. 2th

ed. Saunders Elsevier, 2008: 220 -2.

Johnston G, Sladden M. Scabies: diagnosis and treatment.

BMJ 2005; 331:619 -22.

Global Health - Division of Parasitic Diseases and Malaria.

Parasites - Scabies - Treatment. Centers for Disease Control

and Prevention 2010 (Acedido em: 6 Março 2012). Disponível

em: http://www.cdc.gov/parasites/scabies/treatment.html.

Scott GR, Chosidow O; IUSTI/WHO. European guideline

for the management of scabies, 2010. Int J STD AIDS 2011;

:301 -3.

Heukelbach J, Feldmeier H. Scabies. Lancet 2006; 367:1767-

-74.

Prendiville J. Scabies and Lice. In: Harper J, Oranje A, Prose

N. Harper’s Textbook of Pediatric Dermatology 2nd Ed.

Blackwell Publishing Lt 2005. p 555 -62.

Goldstein B, Goldstein A. Scabies 2012 (Acedido em: 6 Março

. Disponível em: http://www.uptodate.com/contents/

scabies?view=print

Jin SP, Choi JE, Won CH, Cho S. Scabies in a 2 -month -old

Infant Successfully Treated with Lindane. Ann Dermatol 2009;

:200 -2.

Strong M, Johnstone P. Interventions for treating scabies. Cochrane

Database Syst Rev 2007; 3:CD000320.

Walker GJ, Johnstone PW. Interventions for treating scabies.

Cochrane Database Syst Rev 2000; 3:CD000320.

Arlian LG, Runyan RA, Achar S, Estes SA. Survival and infectivity

of Sarcoptes scabiei var. canis and var. hominis. J Am

Acad Dermatol 1984; 11:210 -5.

Karthikeyan K. Treatment of scabies: newer perspectives.

Postgrad Med J 2005; 81:7 -11.

Brooks PA, Grace RF. Ivermectin is better than benzyl benzoate

for childhood scabies in developing countries. J Paediatr

Child Health 2002; 38:401 -4.

Caramona M, Esteves A, Gonçalves J, Macedo T, Mendonça

J, Walter O, et al. Prontuário terapêutico 2011. Medicamentos

usados em afecções cutâneas. Antiparasitários. Sarcoptose

(Sarcoptes scabiei - sarna): 444 -5.

Zargari O, Golchai J, Sobhani A, Dehpour AR, Sadr -Ashkevari

S, Alizadeh N, Darjani A. Comparison of the effi cacy of topical

% lindane vs 5% permethrin in scabies: a randomized,

double -blind study. Indian J Dermatol Venereol Leprol 2006;

:33 -6.

Singalavanija S, Limpongsanurak W, Soponsakunkul S. A

comparative study between 10 per cent sulfur ointment and

3 per cent gamma benzene hexachloride gel in the treatment

of scabies in children. J Med Assoc Thai 2003; 86:S531-

-6.

Ishii N, Asahina A, Amagai M, Iijima M, Ishikawa O, Imamura

H, et al. Guideline for the diagnosis and treatment of scabies

in Japan (second edition). J Dermatol 2008; 35:378 -93.

Bachewar NP, Thawani VR, Mali SN, Gharpure KJ, Shingade

VP, Dakhale GN. Comparison of safety, effi cacy, and cost

effectiveness of benzyl benzoate, permethrin, and ivermectin

in patients of scabies. Indian J Pharmacol 2009; 41:9 -14.

Briones V. Escabiosis. Protocolos de Dermatología. Asociación

Española de Pediatría. 2008: 159 -63 (Acedido em: 6 Março

. Disponível em: http://www.aeped.es/sites/default/

fi les/documentos/escabiosis.pdf

Cook AM, Romanelli F. Ivermectin for the treatment of resistant

scabies. Ann Pharmacother 2003; 37:279 -81.

Buffet M, Dupin N. Current treatments for scabies. Fundam

Clin Pharmacol 2003; 17:217 -25.

Guay DR. The scourge of sarcoptes: oral ivermectin for scabies.

Consult Pharm 2004; 19:222 -35.

Usha V, Gopalakrishnan Nair TV. A comparative study of oral

ivermectin and topical permethrin cream in the treatment of

scabies. J Am Acad Dermatol 2000; 42:236 -40.

Sharma R, Singal A. Topical permethrin and oral ivermectin in

the management of scabies: a prospective, randomized, double

blind, controlled study. Indian J Dermatol Venereol Leprol

; 77:581 -6.

Goldstein B, Goldstein A. Patients information: Scabies 2012

(Acedido em: 6 Março 2012). Disponível: http://www.uptodate.

com/contents/patient -information -scabies

Díaz M, Cazorla D, Acosta M. Effi cacy, safety and acceptability

of precipitated sulphur petrolatum for topical treatment

of scabies at the city of Coro, Falcon State, Venezuela. Rev

Invest Clin 2004; 56:615 -22.

Scabies management. Ottawa, ON: Canadian Paediatric Society.

(Acedido em: 30 Março 2012). Disponível em:

http://www.cps.ca/english/statements/ii/ii01 -01.htm.

Published
2017-01-31
Section
Review Articles