Disseminated tuberculosis in an infant – Case report

Authors

DOI:

https://doi.org/10.25753/BirthGrowthMJ.v32.i2.23772

Keywords:

infant, Mycobacterium tuberculosis, Pediatrics, tuberculosis

Abstract

Infants are a particularly vulnerable group for the development of severe and/or extrapulmonary forms of tuberculosis. The difficulty in establishing a definitive and timely diagnosis contributes to the high morbimortality in this age group. Investigation often relies on a high index of suspicion. Herein is reported a case of disseminated tuberculosis in an infant that highlights its clinical complexity and diagnostic challenge.

Downloads

Download data is not yet available.

References

Berti E; Galli L; Venturini E; de Martini M; Chiapinni E. Tuberculosis in childhood: a systematic review of national and international guidelines. BMC Infectious Diseases. 2014; 14:1471-2334.

Cruz AT; Starke; JR. Pediatric Tuberculosis. Pediatrics in Review. 2010 31;13.

American Thoracic Society. Diagnostic Standards and Classification of Tuberculosis in Adults and Children. Am J Respir Crit Care Med. 2000;161:1376–95.

Leonard JM. Central Nervous System Tuberculosis. Microbiol Spectr 2017; 5.

World Health Organization. Global tuberculosis report 2019. (Assessed August 20; 2020) Available at: https://www.who.int/tb/publications/global_report/en/ (Accessed on march 31; 2020).

Portugal. Ministério da Saúde. Direção-Geral da Saúde. Tuberculose em Portugal - Desafios e Estratégias 2018. Lisboa: Direção-Geral da Saúde; 2018. (Assessed May 15; 2020) Available at: https://www.dgs.pt/portal-da-estatistica-da-saude/diretorio-de-informacao/diretorio-de-informacao/por-serie-963621-pdf.aspx?v=11736b14-73e6-4b34-a8e8-d22502108547.

Direção-Geral da Saúde. Estratégia de vacinação contra a tuberculose com a vacina BCG. Norma nº 006/2016. (Assessed May 29; 2021). Available at: https://www.dgs.pt/directrizes-da-dgs/normas-e-circulares-normativas/norma-n-0062016-de-29062016-pdf.aspx.

Luzzati R.; Migliori G B; Zignol M; Cirillo D M; Maschio M.; Tominz R.; Confalonieri M. Children under 5 years are at risk for tuberculosis after occasional contact with highly contagious patients: outbreak from a smear-positive healthcare worker. European Respiratory Journal. 2017 50(5); 1701414.

Starke JR. New concepts in childhood tuberculosis. Curr Opin Pediatr. 2007 19:306.

Nelson LJ; Wells CD. Global epidemiology of childhood tuberculosis. Int J Tuberc Lung Dis 2004 8:636.

Thomas T A; Heysell S K; Moodley P; Montreuil R; Ha X; Friedland G; Shah S. Intensified specimen collection to improve tuberculosis diagnosis in children from Rural South Africa; an observational study. BMC Infectious Diseases. 2014 14(1).

Schaaf HS; Marais BJ; Carvalho I; et al. Challenges in childhood tuberculosis. In: Migliori GB; Bothamley G; Duarte R; et al.; eds. Tuberculosis (ERS Monograph). Sheffield; European Respiratory Society. 2018 p.234–62.

Stop TB Partnership Childhood TB Subgroup World Health Organization. Guidance for National Tuberculosis Programmes on the management of tuberculosis in children. Chapter 1: introduction and diagnosis of tuberculosis in children. Int J Tuberc Lung Dis 2006; 10:1091.

Lighter J; Rigaud M. Diagnosing childhood tuberculosis: traditional and innovative modalities. Curr Probl Pediatr Adolesc Health Care. 2009 39:61.

Downloads

Published

2023-09-14

How to Cite

1.
Abreu AM, Miranda S, Carvalho I, Gonçalves A, Branco L, Barros D, Pinheiro M. Disseminated tuberculosis in an infant – Case report. REVNEC [Internet]. 2023Sep.14 [cited 2024Jun.21];32(2):122-6. Available from: https://revistas.rcaap.pt/nascercrescer/article/view/23772

Issue

Section

Case Reports

Most read articles by the same author(s)

1 2 > >>