• Maria Miguel Gomes Pediatric Department, Hospital de Braga
  • Ângela Pereira Pediatric Department, Hospital de Braga
  • Ariana Afonso Pediatric Department, Hospital de Braga
  • Helena Silva Pediatric Department, Hospital de Braga
  • Sofia Martins Pediatric Endocrine Group, Hospital de Braga
  • Olinda Marques Pediatric Endocrine Group, Hospital de Braga
  • Ana Antunes Pediatric Endocrine Group, Hospital de Braga




Hypopituitarism, Hypoglycemia, Children.


Introduction: Hypopituitarism is characterized by failure of the pituitary hormone secretion. Clinical presentation is variable and depends on the etiology, evolution and hormonal deficits.

Case: A 2 year-old male child was brought to the emergency room due to sudden change of consciousness. In the neonatal period, he presented with hypoglycemia, thrombocytopenia, jaundice and sepsis with no identified agent. The child showed regular growth (10-25 percentile), adequate psychomotor development and divergent strabismus. The patient was subfebrile with 10 Glasgow Coma Scale. Severe hypoglycemia (26mg/dL) was observed, and it endocrine and metabolic tests were immediately performed that showed low levels of cortisol, and ACTH, GH and TSH deficits. Replacement therapy with hydrocortisone and levothyroxine was started. Neuroimaging showed structural changes with adenohypophysis hypoplasia.

Conclusion: This rare diagnosis demands high degree of suspicion. The progressive development of hormonal deficits requires regular clinical and laboratory evaluations.


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How to Cite

Gomes MM, Pereira Ângela, Afonso A, Silva H, Martins S, Marques O, Antunes A. A CASE OF HYPOGLYCEMIA…. REVNEC [Internet]. 2016Jun.21 [cited 2024May25];25(2):108-12. Available from: https://revistas.rcaap.pt/nascercrescer/article/view/9525



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