Pregnancy Associated Retinal Vascular Events: A Three-Case Series

Authors

DOI:

https://doi.org/10.48560/rspo.43638

Keywords:

Ocular Physiological Phenomena, Pregnancy Complications, Retinal Detachment, Macular Degeneration, Retinal Diseases

Abstract

Pregnancy induces significant systemic and vascular changes that may acutely affect the eye. Some manifestations threaten vision and require multidisciplinary care.

A descriptive case-series of three pregnant women presenting with acute visual loss who un- derwent comprehensive ophthalmologic and systemic evaluation, including multimodal imaging, in close coordination with obstetric teams.

A case with exudative retinal detachment (ERD): A 28-year-old with severe preeclampsia de- veloped bilateral serous detachments that resolved completely after delivery and systemic stabi- lization.

A case with paracentral acute middle maculopathy (PAMM): A 31-year-old at 12 weeks’ gesta- tion presented with a paracentral scotoma in the right eye (OD). Optical coherence tomography (OCT) showed parafoveal hyperreflectivity. Vision remained 1.0, with residual scotoma and with inner nuclear layer (INL) thinning.

A case with Valsalva retinopathy: A 35-year-old at 37 weeks developed a massive subhyaloid hemorrhage in the left eye (OS). Neodymium-doped yttrium aluminum garnet (Nd:YAG) laser hyaloidotomy enabled rapid visual recovery.

Pregnancy-associated retinal vascular events, though rare, reflect distinct pathophysiologic mechanisms and require prompt recognition, multimodal imaging, and coordinated obstetric- ophthalmologic management for optimal outcomes.

Downloads

Download data is not yet available.

References

Naderan M. Ocular changes during pregnancy. J Curr Ophthalmol. 2018;30:202-10. doi: 10.1016/j.joco.2017.11.012.

Nguyen BN, Britten-Jones AC, Bui BV, Walker LE, Titter P. Physiological and pathological changes to the eye and vision during and after pregnancy. Clin Exp Optom. 2025;108:5-13. doi: 10.1080/08164622.2024.2410031.

Hao S, Hao W, Ma Y. The features of serous retinal detachment in preeclampsia viewed on spectral-domain optical coherence tomography. Pregnancy Hypertens. 2024;36:101117. doi: 10.1016/j.preghy.2024.101117.

World Health Organization. Pre-eclampsia. [accessed Sep 2025] Available at: https://www.who.int/news-room/fact-sheets/detail/pre-eclampsia

Pstras L, Thomaseth K, Waniewski J, Balzani I, Bellavre F. The Valsalva manoeuvre: physiology and clinical examples. Acta Physiol. 2016;217:103-19. doi: 10.1111/alpha.12639.

Scott RA, Bhat N, Bindiganavile SH, Li HK, Lee AG. Paracental Acute Middle Maculopathy in Pregnancy. J Neuroophthalmol. 2022;42:e440-2. doi: 10.1097/WNO.0000000000001307.

Vigil-De Gracia P, Ortega-Paz L. Retinal detachment in association with pre-eclampsia, eclampsia, and HELLP syndrome. Int J Gynaecol Obstet. 2011;114:223-5. doi: 10.1016/j.ijgo.2011.04.003.

Downloads

Published

2026-07-11

How to Cite

Justo, S., Reis Silva, A., Francisco, C., Rebelo Neves, E., & Correia Barbosa, R. (2026). Pregnancy Associated Retinal Vascular Events: A Three-Case Series. Revista Sociedade Portuguesa De Oftalmologia. https://doi.org/10.48560/rspo.43638

Issue

Section

Case Reports