Bull ́s Eye Maculopathy in a patient treated with efavirenz

Authors

  • Cristina Vaz Pereira Interno do Internato Complementar de Oftalmologia, Instituto de Oftalmologia Dr. Gama Pinto
  • Mónica Franco Interno do Internato Complementar de Oftalmologia, Instituto de Oftalmologia Dr. Gama Pinto
  • Rita Guerra Pinto Assistente Hospitalar de Oftalmologia do Moorfields Eye Hospital
  • Sandra Barrão Assistente Hospitalar Graduado, Instituto de Oftalmologia Dr. Gama Pinto
  • Helena Prior Filipe Assistente Hospitalar Graduado, Instituto de Oftalmologia Dr. Gama Pinto

DOI:

https://doi.org/10.48560/rspo.6860

Keywords:

Efavirenz, retinal toxicity, HIV, retinal pigment epithelium.

Abstract

Objective: To report a case of retinal toxicity associated with efavirenz in an adult.

Methods: We describe a case of gradual-onset blurry vision in both eyes in a 37-year-old HIV caucasian woman, on antiretroviral therapy (ART), including efavirenz. Results: The patient presented with a best corrected visual acuity of 20/100 for the right eye (RE) and 20/125 for the left eye (LE). Fundoscopy revealed mottled atrophic changes of the macular retinal pigment epi- thelium (RPE) in both eyes. Fluorescein angiography revealed an annular pattern of RPE atrophy in both eyes. Full-field electretinography (ERG) was normal.

Conclusions: Based on our patient ́s history and on previous reports, efavirenz seems to be the culprit in this case. Our report provides evidence in support of routine ophthalmological evalua- tion of patients on efavirenz.

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Published

2015-12-25

How to Cite

Vaz Pereira, C., Franco, M., Guerra Pinto, R., Barrão, S., & Prior Filipe, H. (2015). Bull ́s Eye Maculopathy in a patient treated with efavirenz. Revista Sociedade Portuguesa De Oftalmologia, 39(1), 67–70. https://doi.org/10.48560/rspo.6860

Issue

Vol. 39 No. 1 (2015)

Section

Shot Communications and Images in Ophthalmology

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