Early coronary angiography after out-of-the-hospital cardiac arrest without ST-segment elevation

systematic review protocol


  • Nuno Alves Centro Hospitalar e Universitário de Coimbra, EPE, Coimbra, Portugal https://orcid.org/0000-0002-5550-5976
  • Mauro Mota Instituto Politécnico de Viseu, Escola Superior de Saúde, Viseu, Portugal | Unidade de Investigação em Ciências da Saúde: Enfermagem (UICISA:E) | Unidade Local de Saúde da Guarda, Guarda, Portugal https://orcid.org/0000-0001-8188-6533
  • Joana Ribeiro Centro Hospitalar de Entre o Douro e Vouga, Santa Maria da Feira, Aveiro, Portugal https://orcid.org/0000-0002-1237-3571
  • Madalena Cunha Instituto Politécnico de Viseu, Escola Superior de Saúde, Viseu, Portugal | UICISA:E, ESEnfC, Coimbra / SIGMA – Phi Xi Chapter, ESEnfC, Coimbra, Portugal | CIEC - UM, Braga, Portugal https://orcid.org/0000-0003-0710-9220




out-of-the-hospital cardiac arrest, coronary angiography, ST-segment elevation


Introduction: Coronary artery disease is an important cause of out-of-the-hospital cardiac arrest (OHCA) and coronary angiography often plays a major role in its management. While in the presence of ST-segment elevation (STE) CAG is mandatory within the first 2h, in no-STE OHCA patients there is no consensus on whether early CAG should be performed by default.

Objetives: To assess the impact of early CAG (<24h) in no-STE OHCA patients.

Methods: Herein is described the protocol of a systematic review, which will be developed according to the methodology proposed by the Joanna Briggs Institute. The studies will be analysed and selected for inclusion by two independent reviewers.

Results: The primary endpoint will be short-term survival and the secondary endpoints will include survival with favourable neurological outcomes, mid-term survival and renal adverse events, ventricular arrhythmias and bleeding during hospital stay. This study will analyse and synthetize the evidence concerning the performance of early CAG in no-STE OCHA patients in the context of current clinical practice.

Conclusion: Our results will allow a better planning and standardization of care for no-STE OHCA patients.


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How to Cite

Alves, N., Mota, M., Ribeiro, J., & Cunha, M. (2021). Early coronary angiography after out-of-the-hospital cardiac arrest without ST-segment elevation : systematic review protocol . Millenium - Journal of Education, Technologies, and Health, 2(9e), 189–196. https://doi.org/10.29352/mill029e.25362



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