Interventions in the control of xerostomia in the person in palliative situation
scoping review
DOI:
https://doi.org/10.29352/mill0218.26797Keywords:
xerostomia, dry mouth, palliative care, interventionsAbstract
Introduction: Xerostomia is the subjective sensation of dry mouth; it occurs when less saliva is secreted than the amount of water lost through evaporation and absorption from the oral mucosa. It has multiple consequences for the general and oral health of people in a palliative situation, and quality of life.
Objective: To examine and map the interventions implemented to relieve xerostomia of the person in palliative situation. Methods: A scoping review was conducted following the Joanna Briggs Institute methodology. Data search was performed in the following databases: CINAHL COMPLETE®, PUBMED®, MEDLINE COMPLETE®, SCOPUS® and SciELO®.
Results: A total of 707 articles were identified, and 19 were extracted for final analysis. This scoping review considered the studies focused on people with advanced and irreversible chronic disease, in a palliative situation and at the end of life, aged 18 years or more. Interventions for the control of xerostomia are: non-pharmacological, assessment of the oral cavity, acupuncture, saliva substitutes, saliva stimulants and oral hygiene education programmes; pharmacological parasympathomimetic: pilocarpine and bethanechol chloride.
Conclusion: Xerostomia is a health condition that can cause social embarrassment and chronic discomfort, with a great impact on people's quality of life. Grouping the available evidence, within this theme, can help health professionals to incorporate it into care practice, contributing to the increase in the person’s quality of life and the relief of suffering.
Downloads
References
Al-Shahri, M. Z., Eldali, A. M., & Al-Zahrani, O. (2012). Nonpain symptoms of new and follow-up cancer patients attending a palliative care outpatient clinic in Saudi Arabia. Indian Journal of Palliative Care, 18(2), 98-102. doi:10.4103/0973-1075.100822
Barford, K. L., & D’Olimpio, J. T. (2008). Symptom management in geriatric oncology: Practical treatment considerations and current challenges. Current Treatment Options in Oncology, 9(2–3), 204–214. https://doi.org/10.1007/s11864-008-0062-4
Crogan N.L. (2015). Relieving Drug-Induced Xerostomia with Sorbet. Annals of Long-Term Care (23)2, https://www.hmpgloballearningnetwork.com/
Davies, A. N. (1997). The management of xerostomia: A review. European Journal of Cancer Care, 6(3), 209–214. https://doi.org/10.1046/j.1365-2354.1997.00036.x
Davies, A. N. (2000). A comparison of artificial saliva and chewing gum in the management of xerostomia in patients with advanced cancer. Palliative Medicine, 14(3), 197–203. https://doi.org/10.1191/026921600672294077
Davies, A., Bagg, J., Laverty, D., Sweeney, P., Filbet, M., Newbold, K., De Andrés, J., & Mercadante, S. (2010). Salivary gland dysfunction ('dry mouth’) in patients with cancer: A consensus statement. European Journal of Cancer Care, 19(2), 172–177. https://doi.org/10.1111/j.1365-2354.2009.01081.x
Davies, A., & Hall, S. (2011). Salivary gland dysfunction (dry mouth) in patients with advanced cancer. International Journal of Palliative Nursing, 17(10), 477–482. https://doi.org/10.12968/ijpn.2011.17.10.477
Fleming, M., Craigs, C. L., & Bennett, M. I. (2020). Palliative care assessment of dry mouth: what matters most to patients with advanced disease? Supportive Care in Cancer, 28(3),1121–1129. https://doi.org/10.1007/s00520-019-04908-9
Kahn, S. T., & Johnstone, P. A. S. (2005). Management of xerostomia related to radiotherapy for head and neck cancer. Oncology (Williston Park, N.Y.), 19(14).
Kvalheim, S. F., Marthinussen, M. C., Haugen, D. F., Berg, E., Strand, G. V., & Lie, S. A. (2019). Randomized controlled trial of the effectiveness of three different oral moisturizers in palliative care patients. European Journal of Oral Sciences, 127(6), 523–530. https://doi.org/10.1111/eos.12655
Lopez, G., Garcia, M. K., Liu, W., Spano, M., Underwood, S., Dibaj, S. S., Li, Y., Moguel, R., Williams, J., Bruera, E., & Cohen, L. (2018). Outpatient acupuncture effects on patient self-reported symptoms in oncology care: A retrospective analysis. Journal of Cancer, 9(19), 3613–3619. https://doi.org/10.7150/jca.26527
Lourenço, R. S. P. (2017). Xerostomia e qualidade de vida: tradução e validação da xerostomia related quality of life scale (XeQoLS) para a população portuguesa de cuidados paliativos. http://hdl.handle.net/10451/33971
Meidell, L., & Holritz Rasmussen, B. (2009). Acupuncture as an optional treatment for hospice patients with xerostomia: an intervention study. International Journal of Palliative Nursing, 15(1), 12–20. https://doi.org/10.12968/ijpn.2009.15.1.37947
Mercadante, S., Calderone, L., Villari, P., Serretta, R., Sapio, M., Casuccio, A., & Fulfaro, F. (2000). The use of pilocarpine in opioid-induced xerostomia. Palliative Medicine, 14(6), 529–531. https://doi.org/10.1191/026921600701536273
Mercadante, S., Aielli, F., Adile, C., Ferrera, P., Valle, A., Fusco, F., ... & Porzio, G. (2015). Prevalence of oral mucositis, dry mouth, and dysphagia in advanced cancer patients. Supportive Care in Cancer, 23(11), 3249-3255. doi:10.1007/s00520-015-2720-y
Montgomery-Cranny, J., Hodgson, T., & Hegarty, A. M. (2014). Aetiology and management of xerostomia and salivary gland hypofunction. British Journal of Hospital Medicine, 75(9), 509-514. doi: dx.doi.org/10.12968/hmed.2014.75.9.509
Moore, P. A., & Guggenheimer, J. (2008). Medication-induced hyposalivation: etiology, diagnosis, and treatment. Compendium of Continuing Education in Dentistry (Jamesburg, N.J. : 1995), 29(1), 50–55.
Mortazavi, H., Baharvand, M., Movahhedian, A., Mohammadi, M., & Khodadoustan, A. (2014). Xerostomia due to systemic disease: a review of 20 conditions and mechanisms. Annals of medical and health sciences research, 4(4), 503-510. doi:10.4103/2141-9248.139284
Nieuw Amerongen, A. V., & Veerman, E. C. I. (2003). Current therapies for xerostomia and salivary gland hypofunction associated with cancer therapies. Supportive Care in Cancer, 11(4), 226–231. https://doi.org/10.1007/s00520-002-0409-5
Peters M.D.J., Godfrey C, McInerney P, Munn Z, Tricco AC, & Khalil, H (2020). Chapter 11: Scoping Reviews. In: Aromataris E, Munn Z (Editors). JBI Manual for Evidence Synthesis, JBI. https://synthesismanual.jbi.global. https://doi.org/10.46658/JBIMES-20-12
Plemons, .J. M., Al-Hashimi, I., & Marek, C. L. (2014). American Dental Association Council on Scientific Affairs. Managing xerostomia and salivary gland hypofunction: executive summary of a report from the American Dental Association Council on Scientific Affairs. J Am Dent Assoc.(8):867-73. doi: 10.14219/jada.2014.44. PMID: 25082939.
Reisfield, G. M., Rosielle, D. A., & Wilson, G. R. (2009). Xerostomia, second edition #182. Journal of Palliative Medicine, 12(2), 189–190. https://doi.org/10.1089/jpm.2009.9670
Sheehy, L. (2013). Understanding Factors that influence the grieving process. End of Life Journal, 3(1), 1–9. https://doi.org/10.1136/eoljnl-03-01.1
Sweeney, M. P., Bagg, J., Baxter, W. P., & Aitchison, T. C. (1997). Clinical trial of a mucin-containing oral spray for treatment of xerostomia in hospice patients. Palliative Medicine, 11(3), 225–232. https://doi.org/10.1177/026921639701100307
Towler, P., Molassiotis, A., & Brearley, S. G. (2013). What is the evidence for the use of acupuncture as an intervention for symptom management in cancer supportive and palliative care: An integrative overview of reviews. Supportive Care in Cancer, 21(10), 2913–2923. https://doi.org/10.1007/s00520-013-1882-8
Tricco, A. C., Lillie, E., Zarin, W., O’Brien, K. K., Colquhoun, H., Levac, D., Moher, D., Peters, M. D. J., Horsley, T., Weeks, L., Hempel, S., Akl, E. A., Chang, C., McGowan, J., Stewart, L., Hartling, L., Aldcroft, A., Wilson, M. G., Garritty, C., & Straus, S. E. (2018). PRISMA extension for scoping reviews (PRISMA-ScR): Checklist and explanation. Annals of Internal Medicine, 169(7), 467–473. https://doi.org/10.7326/M18-0850
Twycross, R. (2020). Interview with Dr. Robert Twycross, DM Oxon, FRCP, FRCR, Emeritus Clinical Reader in Palliative Medicine, Oxford University, Oxford, UK by WMJ Editor Peteris Apinis In World Medical Journal. Official Journal of The World Medical Association. Nr.1, vol. 66 ajnuary 2020
World Health Organization (WHO) (2014). Executive Board. Strengthening of palliative care as a component of integrated treatment within the continuum of care [Internet]. Geneve. http://apps.who.int/gb/ebwha/pdf_files/EB134/ B134_R7-en.pdf 30
Worldwide Hospice Palliative Care Alliance (WHPCA) (2020). Global Atlas of Palliative Care. 2nd Edition. ISBN: 978-0-9928277-2-4. http://www.thewhpca.org/resources/global
Venkatasalu, M. R., Murang, Z. R., Ramasamy, D. T. R., & Dhaliwal, J. S. (2020). Oral health problems among palliative and terminally ill patients: An integrated systematic review. BMC Oral Health, 20(1), 1–11. https://doi.org/10.1186/s12903-020-01075-w
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2022 Millenium - Journal of Education, Technologies, and Health
This work is licensed under a Creative Commons Attribution 4.0 International License.
Authors who submit proposals for this journal agree to the following terms:
a) Articles are published under the Licença Creative Commons (CC BY 4.0), in full open-access, without any cost or fees of any kind to the author or the reader;
b) The authors retain copyright and grant the journal right of first publication, allowing the free sharing of work, provided it is correctly attributed the authorship and initial publication in this journal;
c) The authors are permitted to take on additional contracts separately for non-exclusive distribution of the version of the work published in this journal (eg, post it to an institutional repository or as a book), with an acknowledgment of its initial publication in this journal;
d) Authors are permitted and encouraged to publish and distribute their work online (eg, in institutional repositories or on their website) as it can lead to productive exchanges, as well as increase the impact and citation of published work
Documents required for submission
Article template (Editable format)
