Hypotensive effects and physiological mechanisms after a concurrent training session and playful activity in people living with HIV

Abstract

The objective of the present study was to compare BP after a concurrent training session (CT) and playful activities (LA) in people living with HIV (PLHIV) and to analyse the contribution of peripheral resistance and baroreflex in BP. Fifteen people living with HIV participated in the study, 9 women and 6 men aged 50.54 ± 10.81 years, time of ART use of 9.17 ± 4.97 years. All volunteers participated in one session of HT, one session of AL, and one session of control (CC). BP and heart rate (HR) were measured before and after the interventions for analyses of systolic blood pressure (SBP), diastolic blood pressure (DBP), total peripheral resistance (TPR) and low frequency (LF). The Shapiro-Wilk, Friedman, and Wilcoxon tests were performed; the significance level was p<0.05. Spearman's correlation coefficient test and Gohen's test (d) were also used to calculate the effect size. There was a statistically significant decrease in SBP and DBP after TC (SBP: before = 123 ± 14 mmHg; after = 114 ± 8 mmHg; DBP: before = 82 ± 11 mmHg; after = 74 ± 6 mmHg) and AL (SBP: before = 122 ± 15 mmHg; after = 115 ± 10 mmHg; DBP: before = 81 ± 11 mmHg; after = 76 ± 10 mmHg). There was a statistically significant increase in PTR in CC (PTR: before = 14.67 ± 3.06 mmHg·min-1·L; after = 15.57 ± 2.84 mmHg·min-1·L) and a statistically significant decrease in PTR and LF after TC (PTR: before = 15.85 ± 4.48 mmHg·min-1·L; after = 13.48 ± 4.55 mmHg·min-1·L; LF: before = 400.86 ±  376.68 ms²; after = 212.05 ± 252.19 ms²). We can conclude that both HT and AL cause hypotension in PLHIV. Both interventions can be applied to this population in order to improve cardiovascular health.