Imunidade pré-concecional e infeção congénita por citomegalovírus – uma armadilha serológica
DOI:
https://doi.org/10.25753/BirthGrowthMJ.v30.i1.18699Palavras-chave:
citomegalovírus, infeção congénita por citomegalovírus, serologiaResumo
As infeções congénitas por citomegalovírus são as infeções intrauterinas mais prevalentes em todo o mundo e resultam de infeções primárias ou secundárias. O diagnóstico de infeção primária por citomegalovírus durante a gravidez assenta na serologia materna, sendo considerado um método fiável. No entanto, o diagnóstico de infeção secundária é mais complexo. É apresentado o caso de um recém-nascido prematuro de 34 semanas, do sexo masculino, com infeção congénita por citomegalovírus, cuja mãe apresentava imunidade pré-concecional. O diagnóstico no recém-nascido foi confirmado por deteção do vírus na urina através da técnica de PCR (polymerase chain reaction) na primeira semana de vida. A serologia materna periparto foi semelhante à pré-concecional. Este caso alerta para possíveis armadilhas na interpretação da serologia de citomegalovírus na infeção secundária durante a gravidez. Os clínicos devem estar alerta para esta situação e considerar o respetivo diagnóstico, particularmente perante sinais sugestivos de infeção.
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Direitos de Autor (c) 2021 Joana Ferreira, José Luís Fonseca, Maria João Vieira
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