Belantamab Mafodotin Related Keratopathy

Authors

  • Nerea Sáenz Madrazo Department of Ophthalmology, Hospital General Universitario Gregorio Marañón, Madrid, Spain; Department of Immunology, Ophthalmology and Otorhinolaryngology, Faculty of Medicine, Universidad Complutense, Madrid, Spain https://orcid.org/0000-0001-8912-1287
  • Azucena Baeza Department of Ophthalmology, Hospital General Universitario Gregorio Marañón, Madrid, Spain
  • Cristina Encinas Department of Hematology, Hospital General Universitario Gregorio Marañón, Madrid, Spain; Gregorio Marañón Institute of Health Research, Madrid, Spain

DOI:

https://doi.org/10.48560/rspo.27237

Keywords:

Corneal Diseases/ chemically induced, Antibodies, Monoclonal, Humanized/adverse effects

Abstract

 

 

 

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References

Farooq AV, Degli Esposti S, Popat R, Thulasi P, Lonial S, Nooka AK, Jakubowiak A, Sborov D, Zaugg BE, Badros AZ, Jeng BH, Callander NS, Opalinska J, Baron J, Piontek T, Byrne J, Gupta I, Colby K. Corneal Epithelial Findings in Patients with Multiple Myeloma Treated with Antibody-Drug Conjugate Belantamab Mafodotin in the Pivotal, Randomized, DREAMM-2 Study. Ophthalmol Ther. 2020 Dec;9(4):889-911. doi: 10.1007/s40123-020-00280-8. Epub 2020 Jul 25. Erratum in: Ophthalmol Ther. 2020 Sep 12.

Lonial S., Nooka AK., Thulasi P. et al. Management of belantamab mafodotin-associated corneal events in patients with relapsed or refractory multiple myeloma (RRMM). Blood Cancer Journal (2021) 11:103

Marquant K, Quinquenel A, Arndt C, Denoyer A. Corneal in vivo confocal microscopy to detect belantamab mafodotin-induced ocular toxicity early and adjust the dose accordingly: a case report. J Hematol Oncol. 2021 Oct 3;14(1):159. doi: 10.1186/s13045-021-01172-5.

Matsumiya W, Karaca I, Ghoraba H, Akhavanrezayat A, Mobasserian A, Hassan M, Regenold J, Yasar C, Liedtke M, Kitazawa K, Nguyen QD. Structural changes of corneal epithelium in belantamab-associated superficial keratopathy using anterior segment optical coherence tomography. Am J Ophthalmol Case Rep. 2021 Jun 9;23:101133. doi: 10.1016/j.ajoc.2021.101133.

Chuang K, Pineda R, Liu S. Belantamab mafodotin associated corneal microcyst-like epithelial changes. Am J Ophthalmol Case Rep. 2022 Feb 2;25:101392. doi:10.1016/j.ajoc.2022.101392.

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Published

2023-06-29

How to Cite

Sáenz Madrazo, N., Baeza, A., & Encinas, C. (2023). Belantamab Mafodotin Related Keratopathy. Revista Sociedade Portuguesa De Oftalmologia, 47(2), 139–140. https://doi.org/10.48560/rspo.27237

Issue

Section

Shot Communications and Images in Ophthalmology